ID F6B9G7_DESCC Unreviewed; 459 AA.
AC F6B9G7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=D-lactate dehydrogenase (Cytochrome) {ECO:0000313|EMBL:AEF93743.1};
DE EC=1.1.2.4 {ECO:0000313|EMBL:AEF93743.1};
GN OrderedLocusNames=Desca_0863 {ECO:0000313|EMBL:AEF93743.1};
OS Desulfotomaculum nigrificans (strain DSM 14880 / VKM B-2319 / CO-1-SRB)
OS (Desulfotomaculum carboxydivorans).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC Desulfotomaculum.
OX NCBI_TaxID=868595 {ECO:0000313|EMBL:AEF93743.1, ECO:0000313|Proteomes:UP000009226};
RN [1] {ECO:0000313|EMBL:AEF93743.1, ECO:0000313|Proteomes:UP000009226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14880 / VKM B-2319 / CO-1-SRB
RC {ECO:0000313|Proteomes:UP000009226};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Lu M., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Stams A., Plugge C., Muyzer G.,
RA Kuever J., Parshina S., Ivanova A., Nazina T., Woyke T.;
RT "Complete sequence of Desulfotomaculum carboxydivorans CO-1-SRB.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEF93743.1, ECO:0000313|Proteomes:UP000009226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14880 / VKM B-2319 / CO-1-SRB
RC {ECO:0000313|Proteomes:UP000009226};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Lu M., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Stams A., Plugge C., Muyzer G.,
RA Kuever J., Parshina S., Ivanova A., Nazina T., Woyke T.;
RT "Complete sequence of Desulfotomaculum carboxydivorans CO-1-SRB.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; CP002736; AEF93743.1; -; Genomic_DNA.
DR RefSeq; WP_003540134.1; NC_015565.1.
DR AlphaFoldDB; F6B9G7; -.
DR STRING; 868595.Desca_0863; -.
DR KEGG; dca:Desca_0863; -.
DR eggNOG; COG0277; Bacteria.
DR HOGENOM; CLU_017779_9_2_9; -.
DR Proteomes; UP000009226; Chromosome.
DR GO; GO:0004458; F:D-lactate dehydrogenase (cytochrome) activity; IEA:UniProtKB-EC.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2740; -; 1.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR PANTHER; PTHR42934; GLYCOLATE OXIDASE SUBUNIT GLCD; 1.
DR PANTHER; PTHR42934:SF2; GLYCOLATE OXIDASE SUBUNIT GLCD; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000313|EMBL:AEF93743.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009226}.
FT DOMAIN 37..217
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
SQ SEQUENCE 459 AA; 48832 MW; 26ABA316725ED97F CRC64;
MAKAQVIDAL IQALGKEKVV TDPEDLICYS FDATADMPSK LPDVVVVPAS TNEVVQIINI
AREYKVPVYP RGSGTNLSGG TIPIQGGIVV SMQGMNKILE IDADNLVAVV QPGVVIQDLN
NAVAPFGLIY PPDPGTVATA TMGGSVSECS GGLRGLKYGV TKHYVMGLEV VLADGSVARF
GGKTVKNVTA YDMVKLFTGA EGTLGIITEI TVKLIPAPEA RKSMLAIFNN LADAGNTVTE
IVRSKVIPAT MEIMDKVTIQ TVENFAKVGL PTNAEALLLI EVDGIPEVVE REAAIVVKVV
EKNKGKIQVA KDDKERDGLW AARRAALPAL AQVKPTTVLE DATVPRSKIT EMLVALQDIA
KKYNLQIGTF GHAGDGNLHP TILTDARDTE EMERVHQAVD EIFKTALSLG GTISGEHGIG
MAKAKYLPLE FGDSGMEAMR KVKQALDPDN LLNPGKMLN
//
