ID F6D8X2_THICA Unreviewed; 609 AA.
AC F6D8X2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=von Willebrand factor type A {ECO:0000313|EMBL:AEG31972.1};
GN OrderedLocusNames=Thicy_1205 {ECO:0000313|EMBL:AEG31972.1};
OS Thiomicrospira cyclica (strain DSM 14477 / JCM 11371 / ALM1)
OS (Thioalkalimicrobium cyclicum).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Thiomicrospira.
OX NCBI_TaxID=717773 {ECO:0000313|EMBL:AEG31972.1, ECO:0000313|Proteomes:UP000009232};
RN [1] {ECO:0000313|EMBL:AEG31972.1, ECO:0000313|Proteomes:UP000009232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14477 / JCM 11371 / ALM1
RC {ECO:0000313|Proteomes:UP000009232};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Davenport K., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Kappler U., Woyke T.;
RT "Complete sequence of Thioalkalimicrobium cyclicum ALM1.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002776; AEG31972.1; -; Genomic_DNA.
DR AlphaFoldDB; F6D8X2; -.
DR STRING; 717773.Thicy_1205; -.
DR KEGG; tcy:Thicy_1205; -.
DR eggNOG; COG2304; Bacteria.
DR HOGENOM; CLU_420873_0_0_6; -.
DR OrthoDB; 9807628at2; -.
DR Proteomes; UP000009232; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR22550:SF5; LEUCINE ZIPPER PROTEIN 4; 1.
DR PANTHER; PTHR22550; SPORE GERMINATION PROTEIN; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009232};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 101..301
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 468..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 67518 MW; 390900EA60122871 CRC64;
MNGGAEMVIA ELFFRQASWL SLLLPWLAGL LIWLAYRRRQ ATEYSDEALQ PWALASRAPA
SYWPWRWPLG FWIGVLLLVA LAGPRWALES PTMPTQSQGV NHLVLLDASR SMTAQDRHPD
RFAHAQNLLA AWAQRLPAED RVGLMLFGTE AYWALPMTQD KVLLQDRLGL LQAQRLPFAG
TQLDVALRQG LAAAQAQGVQ QLVLVTDGVL ASQNESLMAV AAAIAAADVS LLVVGVGTSD
PVALPDSASP TGWLVYDGLR VTVPMERQAL QRLAQAADGR YVDDRNQTAQ LQAWLDYDDR
LVGQAIRDDE LVDGIEQLQA YYDLTPWIVM ALLAGLLWLF AVPRVAVGTT TGLLLSVTLV
SFLSVMASSA VWANPPADYV RWMQAGEQQH RAQQHPQAQG YFRQALLTAR NAEERARSLY
NLGLSYADQQ AWSLAVEALE GALIHQSDFP EAAHNLALAQ RQQALQLAAQ ARQDQDGEQQ
QEQGENGQGA GRDGNDDPTL AGATDGENWG RDDDEDYWGE DLPEREGQLA ELPPEQQELS
SSRGAWQGQA VIEQQRLDFA REQRQADLQR YLQQIEDDQV GILFHLFERE AGFQARQSQQ
VELPGVKPW
//
