ID F6DHS2_THETG Unreviewed; 648 AA.
AC F6DHS2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=V-type ATP synthase subunit I {ECO:0000256|RuleBase:RU361189};
GN OrderedLocusNames=Ththe16_1290 {ECO:0000313|EMBL:AEG33693.1};
OS Thermus thermophilus (strain SG0.5JP17-16).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=762633 {ECO:0000313|EMBL:AEG33693.1, ECO:0000313|Proteomes:UP000009233};
RN [1] {ECO:0000313|EMBL:AEG33693.1, ECO:0000313|Proteomes:UP000009233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG0.5JP17-16 {ECO:0000313|EMBL:AEG33693.1,
RC ECO:0000313|Proteomes:UP000009233};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Allgaier M., Hugenholtz P., Singer S.,
RA Gladden J., Woyke T.;
RT "Complete sequence of chromosome of Thermus thermophilus SG0.5JP17-16.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000009233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG0.5JP17-16 {ECO:0000313|Proteomes:UP000009233};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Allgaier M., Hugenholtz P., Singer S.,
RA Gladden J., Woyke T.;
RT "Complete sequence of chromosome of Thermus thermophilus SG0.5JP17-16.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
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DR EMBL; CP002777; AEG33693.1; -; Genomic_DNA.
DR AlphaFoldDB; F6DHS2; -.
DR KEGG; tts:Ththe16_1290; -.
DR PATRIC; fig|762633.3.peg.1279; -.
DR HOGENOM; CLU_025558_2_1_0; -.
DR Proteomes; UP000009233; Chromosome.
DR GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR Gene3D; 1.20.1460.20; -; 1.
DR Gene3D; 3.30.70.2170; -; 1.
DR Gene3D; 3.30.70.2750; -; 1.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR InterPro; IPR040574; V_ATPase_I_N.
DR InterPro; IPR041276; V_ATPase_prox.
DR PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 1.
DR Pfam; PF18670; V_ATPase_I_N; 1.
DR Pfam; PF18274; V_ATPase_prox; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 349..371
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 402..421
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 458..483
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 495..513
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 519..537
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 558..581
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 587..610
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT DOMAIN 1..52
FT /note="Vacuolar ATPase subunit I N-terminal proximal lobe"
FT /evidence="ECO:0000259|Pfam:PF18274"
FT DOMAIN 112..200
FT /note="V-type ATP synthase subunit I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18670"
FT COILED 94..121
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 648 AA; 71751 MW; D2435E5032F002E4 CRC64;
MEKLVLAGPK GRAKELLQSL QQAGVVHLET LRPEALSAYQ LSPEERAELR RWEAVSAGAE
HTLSLLGLEA EPARPFPEGL EAAEKALSPI QAHAEGLTRQ KQELEEELAL AQAYLEPLER
LAALAHGLDK SPFLRVIPFL LTEKELPLVE EALRKALEDR YLLAHEAYAG GVAALVVVHR
KEVDQAKAAL SRAGVAELRL PGALGELSLS EVAKRLKERA EAAPRELSEV RQHLAKLARE
SASTLQSLWT RAQDEVARLK ALEELASGRF GFALLGYVPV KAKPKVEEAL ARHKESVVYA
FEPVDEHHEA DRIPVVLDNP PWVKPFELLV SFLNTPKYGT FDPTPVVPIF FPFWFGMIVG
DIGYALLFYL VGRWLSGYVK RNEPLVIDLF ALKLKPQVIG KLVYILNWMV FWTVVWGVIY
GEFFGTFLEH LGVFGTPEHP GLIPILIHRI DTAKTANLLI LLSVAFGVVL VFFGLALRAY
LGLKHRHMAH FWEGVGYLGG LVGVLALAAS YLGNLQAGWL QGLMYLGFGV FLLAVLMSRI
WLMIPEIFTQ AGHILSHIRI YAVGAAGGIL AGLLTDVGFA IAERLGLVGV LLGLLVAGVL
HLLILLLTTL GHMLQPIRLL WVEFFTKFGF YEENGRPYRP FKSVREAQ
//
