ID F6EPX8_HOYSD Unreviewed; 704 AA.
AC F6EPX8;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Possible membrane protein {ECO:0000313|EMBL:AEF41799.1};
GN OrderedLocusNames=AS9A_3358 {ECO:0000313|EMBL:AEF41799.1};
OS Hoyosella subflava (strain DSM 45089 / JCM 17490 / NBRC 109087 / DQS3-9A1)
OS (Amycolicicoccus subflavus).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Hoyosellaceae;
OC Hoyosella.
OX NCBI_TaxID=443218 {ECO:0000313|EMBL:AEF41799.1, ECO:0000313|Proteomes:UP000009235};
RN [1] {ECO:0000313|EMBL:AEF41799.1, ECO:0000313|Proteomes:UP000009235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45089 / DQS3-9A1 {ECO:0000313|Proteomes:UP000009235};
RX PubMed=21725023; DOI=10.1128/JB.05388-11;
RA Cai M., Chen W.M., Nie Y., Chi C.Q., Wang Y.N., Tang Y.Q., Li G.Y.,
RA Wu X.L.;
RT "Complete genome sequence of Amycolicicoccus subflavus DQS3-9A1T, an
RT actinomycete isolated from crude oil-polluted soil.";
RL J. Bacteriol. 193:4538-4539(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR EMBL; CP002786; AEF41799.1; -; Genomic_DNA.
DR RefSeq; WP_013808148.1; NC_015564.1.
DR AlphaFoldDB; F6EPX8; -.
DR STRING; 443218.AS9A_3358; -.
DR KEGG; asd:AS9A_3358; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_4_1_11; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000009235; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009235};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 164..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..536
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 617..637
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 195..325
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 704 AA; 73681 MW; DFFAE33A564873BB CRC64;
MNTGTRNIRW LLPALLLVAW LVLGGVAGPF AGKLGEVQVN DAAAFLPQSA ESTEVQDLQR
LFSDTTAIPA IVIAEREGGT EDADFAFLAD TVEDAVQGER FAGPPSPPIP SSDGQAIQII
VPVDANGSVA DAVDELRDGF VGAPDGLNVF VTGPAGSSAD LGAAFAGIDG LLLIVAAVVV
IVILVIVYRS PLLPFIVVLS AILALALASL VVYLLADAGT VTLNGQSQGI LFILVFGAAT
DYALLLVARF REELRTSTDR FSAMLRAWRA ALPPIAASAG TVVAGVLCLL LSDLNSNRSL
GPIAAIGITA SFIATMTFLA AILTLLGRSA YWPSRPRFSP NADSETFRNY RFWAALAKRI
EAHPRRYWTV PLIVVLAFAA CLPLLRADGV AQSEIFLLQV ESQEGQQALE RHFDAGAGSP
AIIIANETAG DEVLAAAQIE GVADAVLLRD GASGEPLVRD GLVQIEATFA APADSAEAED
VLRELRSAVA GVEGAEAKVG GPTAVQIDTN DTSKRDRALI MPLVLLVVFA ILAVLLRALV
APLFLIGTVV ISFAATLGVS ALVFNYALGF PGADPVIPLF AFVFLVALGI DYNIFLMTRA
REEALQIGTR DGVLRSLVVT GGVITSAGIV LAATFAALSV IPLIFMVQIA FIVAFGVLLD
ALIMRSLIVP AVVREAGPMI WWPGSLSREA VSSPDKTAAV PSPR
//
