ID F6H9F4_VITVI Unreviewed; 828 AA.
AC F6H9F4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN OrderedLocusNames=VIT_04s0069g00390 {ECO:0000313|EMBL:CCB48847.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB48847.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; FN595500; CCB48847.1; -; Genomic_DNA.
DR AlphaFoldDB; F6H9F4; -.
DR STRING; 29760.F6H9F4; -.
DR PaxDb; 29760-VIT_04s0069g00390-t01; -.
DR EnsemblPlants; Vitvi04g00712_t001; Vitvi04g00712_P001; Vitvi04g00712.
DR Gramene; Vitvi04g00712_t001; Vitvi04g00712_P001; Vitvi04g00712.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_0_2_1; -.
DR InParanoid; F6H9F4; -.
DR Proteomes; UP000009183; Chromosome 4.
DR ExpressionAtlas; F6H9F4; baseline.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966:SF450; GLUTAMATE RECEPTOR 2.8-RELATED; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT TRANSMEM 474..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 720..743
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 351..698
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 788..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..828
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 646..702
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 828 AA; 92402 MW; DA45F18B00F55611 CRC64;
MQANFMIGLG SKARVPIISF SATSPSLSWL QSQYFIRATL NDSAQVPAIR AIVQAFGWRE
VVLIYVDNEY GNGVVPSLTS ALQEVDTHVT YRSAIHPSAT DDQIVKELYK LMTMSTRVFI
VHMLTPLGSQ LFTKANEAGM MEEGYVWILT DGITDFLSTL DASAIDSMQG VLGVKPHVPR
TKKLESFKIR WKKKIQEEYP TNEISELNIF GLWAYDAASA LAMAFEKLGA GNFSLQKTNI
SRDSTGFESI RVSPVGPNIL HSLLSTRFRG LSGDFQIFDG QLHSTAFQIV NVIGKGERGV
GFWTPKNGII RRLNFTNTYS TSKDNLGIIV WPGEPTYVPK GWVLPVNEKL KIGVPVNAFS
EFVNVTWDPK TNATKVTGYC IDVFDEVMRS LPYAVPYEYI PFGTPDGKSA GSYNDLIYQV
FLKNYDAVVG DTTIVANRSK YVDFTLPYTE SGVSMIVPIK DNKSKSAWIF LKPLTWDLWV
TSACFFVFIG FVIWVLEHRI NEDFRGPHSH QAGTIFWFSF TTMMFAQKER IMSNLARFVM
IIWFFVVLIL TQSYTASLTS MLTVQQLQPT VTDIKELQAK REYVGYQQDS FVLEFLKRMK
FDESKLRIYS SPEKLAELFS KGSANGGIAA AFDEIPYMKL FIAQHCSKYT MVQPIYKFDG
FGFAFPIGSP LVPDVSRAVL IVTEGNEMVR IEKKWFSEKT SCSDDNGSLL SSNNISLDSF
WGLFLIAGVT SSLALIIGIA MFLHKHRVVV MGKDSASTKI KTLMTLFDQK DLSSHTFRIA
DQPYSGSNEP IAAVGASPSV TNSSPRPSTF SNQTNNDIPL SGEQGTSS
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