ID F6I0B4_VITVI Unreviewed; 418 AA.
AC F6I0B4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Protein PIN-likeS 1 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_04s0044g01850 {ECO:0000313|EMBL:CCB60380.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB60380.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- FUNCTION: Involved in cellular auxin homeostasis by regulating auxin
CC metabolism. Regulates intracellular auxin accumulation at the
CC endoplasmic reticulum and thus auxin availability for nuclear auxin
CC signaling. {ECO:0000256|ARBA:ARBA00025100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
CC {ECO:0000256|ARBA:ARBA00025752}.
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DR EMBL; FN596506; CCB60380.1; -; Genomic_DNA.
DR RefSeq; XP_002264606.1; XM_002264570.3.
DR RefSeq; XP_003631924.1; XM_003631876.3.
DR AlphaFoldDB; F6I0B4; -.
DR PaxDb; 29760-VIT_04s0044g01850-t01; -.
DR EnsemblPlants; Vitvi04g01746_t001; Vitvi04g01746_P001; Vitvi04g01746.
DR EnsemblPlants; Vitvi04g01746_t003; Vitvi04g01746_P003; Vitvi04g01746.
DR GeneID; 100253302; -.
DR Gramene; Vitvi04g01746_t001; Vitvi04g01746_P001; Vitvi04g01746.
DR Gramene; Vitvi04g01746_t003; Vitvi04g01746_P003; Vitvi04g01746.
DR KEGG; vvi:100253302; -.
DR eggNOG; KOG2722; Eukaryota.
DR HOGENOM; CLU_044945_0_0_1; -.
DR InParanoid; F6I0B4; -.
DR OrthoDB; 297188at2759; -.
DR Proteomes; UP000009183; Chromosome 4.
DR ExpressionAtlas; F6I0B4; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0080162; P:endoplasmic reticulum to cytosol auxin transport; IEA:InterPro.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR InterPro; IPR045033; PILS1/3/4/5/7.
DR PANTHER; PTHR31651:SF6; PROTEIN PIN-LIKES 3-LIKE ISOFORM X1; 1.
DR PANTHER; PTHR31651; TRANSPORTER; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 205..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 45364 MW; B354D04A62E97E18 CRC64;
MGFWSLFVTA LMPILKVLVV TGIGLFIALE RIDLLGPTAR HHLNTLVFYI FYPALVASNL
ADTVTASSLA TMWFMPVNIL LTFIIGSALG WILIKITRPP QHLHALILGC CSAGNMGNLF
FIIIPAICEE SDNPFGSSDC STDGDAYASL SSALGAIGVW TYVYMIMRMS ATKCKGEINL
CNSTTSVRTS REALEISSDC CTEALLPPRD SPRSGNWSDE EELPHDGSEE KSEVPFSEKI
KQKVKIFMEK TNFKQVFTPS TIGVIFGFFI GLIPPIRKLI IGDSAPLRVI ESSATLLGEA
AIPSTTLIMG ANLLSGLKGS DVSIVVILGI VAVRYIFLPL LGVVVVKAAT HFGLVGSNLL
FQFVLMLQYA VPPAMGTGVI CQLFQFGQSE CSVIMLWTYA VAGFALTLWS TFFMWLVS
//
