ID F6I0K7_VITVI Unreviewed; 538 AA.
AC F6I0K7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00497, ECO:0000259|PROSITE:PS00498};
GN OrderedLocusNames=VIT_03s0038g04730 {ECO:0000313|EMBL:CCB60473.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB60473.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR EMBL; FN596508; CCB60473.1; -; Genomic_DNA.
DR AlphaFoldDB; F6I0K7; -.
DR STRING; 29760.F6I0K7; -.
DR PaxDb; 29760-VIT_03s0038g04730-t01; -.
DR EnsemblPlants; Vitvi03g00312_t001; Vitvi03g00312_P001; Vitvi03g00312.
DR Gramene; Vitvi03g00312_t001; Vitvi03g00312_P001; Vitvi03g00312.
DR eggNOG; ENOG502QVTH; Eukaryota.
DR HOGENOM; CLU_029668_1_0_1; -.
DR InParanoid; F6I0K7; -.
DR Proteomes; UP000009183; Chromosome 3.
DR ExpressionAtlas; F6I0K7; baseline and differential.
DR GO; GO:0004097; F:catechol oxidase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR022740; Polyphenol_oxidase_C.
DR InterPro; IPR022739; Polyphenol_oxidase_cen.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF76; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF12142; PPO1_DWL; 1.
DR Pfam; PF12143; PPO1_KFDV; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Thioether bond {ECO:0000256|ARBA:ARBA00022784}.
FT DOMAIN 132..149
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
FT DOMAIN 289..300
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 538 AA; 62129 MW; 12A08D4FB7BC9946 CRC64;
MILGISVGEI SPQHHDVDAK KHAKNVVSPN LTTCHESVPR PGLSVYCCPP KPESEEPFID
FQFPDPSSPL RLRRAAHLVD DDYIAKYRNA VSIMKSLPYD DPRSFLSQAN LHCIYCTGAY
KQKNSDIPLH VHRSWLFFPW HRMMLYFHER ILGSLIGDDS FALPFWNWDN PDGMVIPEMY
VTGSLVDTDR ENSHLPPQVV DLNYNLQEKG LGPEEQIKIN MALMYTQMVS GAKTTELFMG
CPYKGGEGGF CEGPGTIELA PHNTLHDWTG TGLNPGREDM GSFYSAGRDP IFYGHHGNVD
RLWEVWRRLQ WEYYNSEITD TEWLDSYFFF HDEKRQLVRI KFQDVVNITR LRYAYEEVEL
PWLNARPRPS VPPKIARDIL KMRDLDHENN QELPSSPFLS ADFGPHGRTL DTTIRVKVHR
PKKHRSKKQK DFKEEEVMVV YGIEVKEDSY VKFDVYVNAV DETLMVGPEF REFAGTFVNI
PIGVWPVMRR KSNLKLGISE LLQDLEADED ESIWVTLIPR AEDCMNVTID GIRIEYIE
//
