ID F6I7R1_VITVI Unreviewed; 389 AA.
AC F6I7R1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
DE Flags: Fragment;
GN ORFNames=VIT_00s2240g00010 {ECO:0000313|EMBL:CCB62981.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
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DR EMBL; FN596941; CCB62981.1; -; Genomic_DNA.
DR AlphaFoldDB; F6I7R1; -.
DR HOGENOM; CLU_007383_1_2_1; -.
DR Proteomes; UP000009183; Unassembled WGS sequence, unordered.
DR ExpressionAtlas; F6I7R1; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR PANTHER; PTHR43574:SF24; NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01370; Epimerase; 1.
DR PRINTS; PR01713; NUCEPIMERASE.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..334
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT NON_TER 389
FT /evidence="ECO:0000313|EMBL:CCB62981.1"
SQ SEQUENCE 389 AA; 43238 MW; 73ABD6E6F1DE73B2 CRC64;
MSQHMDNIPS TPGKFKSDKY HYIHRFRSHS SLAKLILWSL FFFSVICFFF LLSPTSPTSP
PADRSRRVLA NYTWGGPEWE KKVRQSARVR SDHGHTVLVT GGAGFVGSHV SAALKRRGDG
VIGLDNFNNY YDPELKRHRR DLLERAGVFV VEGDINDSEL LRKLFDVVAF THVMHLAAQA
GVRYAMQNPK SYVNSNIAGL VNLLEVCKSA DPQPAIVWAS SSSVYGLNSK VPFSEKDRTD
RPASLYAATK KAGEAIAHTY NHIYGLSITG LRFFTVYGPW GRPDMAYFFF TRDILTGKPI
TIFEGPDHGS VARDFTYIDD IVKGCLASLD TAKKSTGTGG KKKGAAQFRI FNLGNTSPVD
VSKLVSILEK LLKVKAKRRV LPMPRNGDV
//
