ID F6IIH2_9SPHN Unreviewed; 487 AA.
AC F6IIH2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=GntR family transcriptional regulator / MocR family aminotransferase {ECO:0000313|EMBL:CCA91614.1};
GN ORFNames=PP1Y_AT6650 {ECO:0000313|EMBL:CCA91614.1};
OS Novosphingobium sp. PP1Y.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=702113 {ECO:0000313|EMBL:CCA91614.1, ECO:0000313|Proteomes:UP000009242};
RN [1] {ECO:0000313|EMBL:CCA91614.1, ECO:0000313|Proteomes:UP000009242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sp. PP1Y {ECO:0000313|Proteomes:UP000009242};
RX PubMed=21685292; DOI=10.1128/JB.05349-11;
RA D'Argenio V., Petrillo M., Cantiello P., Naso B., Cozzuto L., Notomista E.,
RA Paolella G., Di Donato A., Salvatore F.;
RT "De novo sequencing and assembly of the whole genome of Novosphingobium sp.
RT strain PP1Y.";
RL J. Bacteriol. 193:4296-4296(2011).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FR856862; CCA91614.1; -; Genomic_DNA.
DR RefSeq; WP_013832042.1; NC_015580.1.
DR AlphaFoldDB; F6IIH2; -.
DR KEGG; npp:PP1Y_AT6650; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_1_5; -.
DR OrthoDB; 9808770at2; -.
DR Proteomes; UP000009242; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:CCA91614.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000009242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:CCA91614.1}.
FT DOMAIN 19..87
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 487 AA; 53663 MW; 292EFF2B49069941 CRC64;
MLRPWQVTLS ERIDPERGTP IYMQIIHALI RDIETGRLTS GTFLPSSREL AGALGVNRKT
VVLAYEDLIA QGWLSTEGTR GTMVSRSLPS SPSGEPSVEA GARFDQALYR FAEAPDRPLA
LPGGKGIKLD EGAPDGRLFP ADQLARAYRS AISRASRSNR LQYRDPRGSE GLREQVAEML
RTQRGLPVSM ENICITRGSQ NGLFLALQVL IEPGDTVIVE ELTYEPAVAA IRALGGKVIP
VGLDEEGINV AEVEECCRRH AVRAIFLTPH HQFPTTVALR PERRLQLLDL ARQFGVAIIE
DDYDHEFHFQ SQPLLPMAGY APAQVIYLGS MSKLLLPALR IGYMAAPEKV IDAIAHRVSL
TDGMGNTVTE DAAAELIRSG EVRRHARKAW RVYSERRESF ARLLHEHLGE HCSFAVPDGG
LAFWLRFSGD LDLIEARARE QGLRFASHRS FMARDTAAKG MRLGFASLNE AEAERAIAAL
AAATRAD
//
