ID F6IVK6_LACPE Unreviewed; 1033 AA.
AC F6IVK6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=DNA translocase FtsK {ECO:0000256|ARBA:ARBA00020887};
GN ORFNames=LPE_01671 {ECO:0000313|EMBL:CCB82644.1};
OS Lactiplantibacillus pentosus MP-10.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1028490 {ECO:0000313|EMBL:CCB82644.1};
RN [1] {ECO:0000313|EMBL:CCB82644.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MP-10 {ECO:0000313|EMBL:CCB82644.1};
RX PubMed=21705590; DOI=10.1128/JB.05171-11;
RA Abriouel H., Benomar N., Perez Pulido R., Canamero M.M., Galvez A.;
RT "Annotated genome sequence of Lactobacillus pentosus MP-10, which has
RT probiotic potential, from naturally fermented Alorena green table olives.";
RL J. Bacteriol. 193:4559-4560(2011).
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; FR871806; CCB82644.1; -; Genomic_DNA.
DR AlphaFoldDB; F6IVK6; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF42; DNA TRANSLOCASE SFTA; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000313|EMBL:CCB82644.1};
KW Cell division {ECO:0000313|EMBL:CCB82644.1};
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}.
FT DOMAIN 699..891
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 22..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 360..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 716..723
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1033 AA; 109151 MW; 18922BD1BD6BDA81 CRC64;
MKMNHYDGPA FFRKYRYNQR QMNNSAASQS TPTAVSASSQ AASSAASAVE TPARAASPVR
SSSAGADTTT LFNGGTHGDF HPSRVPAQLT SALTNGGIIQ DNDDRNYLEI QASLHKRPES
FLLFADETTA DLPLVDLQAP QTSASSFSQT PLSQAPSNKA DSAMSNEPTR QSMAATSANA
SEATATAEQS AATSQATVAI ASAAPTEVFE PSDPELAVSA AAVNQSRVTE PQVARPTEIF
EPSDPELAAS AAAVNQSHVA EPQVARPTEV FEPSAPELAA SAAAINQSHV AEPQVARPTE
VFEPSDPELA ASAAQVNAQS ADSTTDARSE SAAAKPAHGL GLSLGDIMTA EHDAQADLAL
FKDQPATTSE AAAPVSSAAK TSDANRLVSA AADSATQESE VTDQHSSEVT EYSEVPVGSE
ASDESDDFNG QAQSTSNTEA GSQSTDSITH NNGSGGASTA PRSQAPQPDE LYQPVGMRPA
SSTAVTPVST TASATTSATS VHQSHADTTT GNRPAPSTAA TSAVTAPTPH ATVEQTSDED
QPELVHSGES AAPVLEDKEL AAYHLPPLNL LKAPIVPNES EMDDWIEQKA SALDESLDAF
GVNANVVDWT IGPTVTQFQV KLARGVKVSK ITNLNDDLKL ALAAKDIRIE APIPGRNTVG
IEIPNMKSRP VMLSEVLDTD KFRQSKSPLT VALGVDLFGK PQVTDLRKMP HGLIAGATGS
GKSVFINSIL VSILYKANPQ QVKLLLIDPK AVELAPYNEI PHLLAPVISE PKAASAALKW
VVDEMDNRYD KLAAGGARNI EQFNQLAEEH HEPGLKMPYI VIVIDELADL MMVASSEVQD
YIARITQKAR AAGIHLLVAT QRPSVDVVTG LIKNNIPTRV AFMVASQIDS RTILDSSGAE
RLLGRGDMLY LGNGQSNAVR LQGTFVDSEI DSITQFVRDQ AAPHYEFQPD SLLKHEEAAR
NEDDLMPEAL AYIANEDTMS TSKLQRNFSI GYNRAANIID DLENRGYVSA AKGSKPRDVY
FTADDLTKLQ ANS
//
