ID F6JD10_DROYA Unreviewed; 348 AA.
AC F6JD10;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
GN Name=CG1554 {ECO:0000313|EMBL:ADG48684.1};
OS Drosophila yakuba (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7245 {ECO:0000313|EMBL:ADG48684.1};
RN [1] {ECO:0000313|EMBL:ADG48684.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NY137 {ECO:0000313|EMBL:ADG48679.1}, NY141
RC {ECO:0000313|EMBL:ADG48680.1}, NY20 {ECO:0000313|EMBL:ADG48681.1},
RC NY42 {ECO:0000313|EMBL:ADG48682.1}, NY48
RC {ECO:0000313|EMBL:ADG48683.1}, NY57 {ECO:0000313|EMBL:ADG48684.1},
RC NY60 {ECO:0000313|EMBL:ADG48685.1}, NY65
RC {ECO:0000313|EMBL:ADG48686.1}, NY66 {ECO:0000313|EMBL:ADG48687.1},
RC NY70 {ECO:0000313|EMBL:ADG48688.1}, NY71
RC {ECO:0000313|EMBL:ADG48674.1}, NY73 {ECO:0000313|EMBL:ADG48675.1},
RC NY75 {ECO:0000313|EMBL:ADG48676.1}, NY83
RC {ECO:0000313|EMBL:ADG48677.1}, and NY85 {ECO:0000313|EMBL:ADG48678.1};
RA Andolfatto P.;
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
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DR EMBL; GQ313384; ADG48674.1; -; Genomic_DNA.
DR EMBL; GQ313385; ADG48675.1; -; Genomic_DNA.
DR EMBL; GQ313386; ADG48676.1; -; Genomic_DNA.
DR EMBL; GQ313387; ADG48677.1; -; Genomic_DNA.
DR EMBL; GQ313388; ADG48678.1; -; Genomic_DNA.
DR EMBL; GQ313389; ADG48679.1; -; Genomic_DNA.
DR EMBL; GQ313390; ADG48680.1; -; Genomic_DNA.
DR EMBL; GQ313391; ADG48681.1; -; Genomic_DNA.
DR EMBL; GQ313392; ADG48682.1; -; Genomic_DNA.
DR EMBL; GQ313393; ADG48683.1; -; Genomic_DNA.
DR EMBL; GQ313394; ADG48684.1; -; Genomic_DNA.
DR EMBL; GQ313395; ADG48685.1; -; Genomic_DNA.
DR EMBL; GQ313396; ADG48686.1; -; Genomic_DNA.
DR EMBL; GQ313397; ADG48687.1; -; Genomic_DNA.
DR EMBL; GQ313398; ADG48688.1; -; Genomic_DNA.
DR AlphaFoldDB; F6JD10; -.
DR EnsemblMetazoa; FBtr0263810; FBpp0262302; FBgn0084295.
DR GO; GO:0005703; C:polytene chromosome puff; IEA:EnsemblMetazoa.
DR GO; GO:0005665; C:RNA polymerase II, core complex; IEA:EnsemblMetazoa.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02584; RNAP_II_Rpb1_C; 1.
DR Gene3D; 3.30.1360.140; -; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR007073; RNA_pol_Rpb1_7.
DR InterPro; IPR038593; RNA_pol_Rpb1_7_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..74
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04992"
FT DOMAIN 75..347
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
FT DOMAIN 159..294
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04990"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADG48684.1"
FT NON_TER 348
FT /evidence="ECO:0000313|EMBL:ADG48684.1"
SQ SEQUENCE 348 AA; 39461 MW; FFAD48698622F6FA CRC64;
PMRVIKGVKG LLERCVIVTG NDRISKQANE NATLLFQCLI RSTLCTKYVS EEFRLSTEAF
EWLIGEIETR FQQAQANPGE MVGALAAQSL GEPATQMTLN TFHFAGVSSK NVTLGVPRLK
EIINISKKPK APSLTVFLTG GAARDAEKAK NVLCRLEHTT LRKVTANTAI YYDPDPQRTV
ISEDQEFVNV YYEMPDFDPT RISPWLLRIE LDRKRMTDKK LTMEQIAEKI NVGFGEDLNC
IFNDDNADKL VLRIRIMNNE ENKFQDEDEA VDKMEDDMFL RCIEANMLSD MTLQGIEAIG
KVYMHLPQTD SKKRIVITET GEFKAIGEWL LETDGTSMMK VLSERDVD
//
