ID F6QBM1_HORSE Unreviewed; 217 AA.
AC F6QBM1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Large ribosomal subunit protein uL22m {ECO:0000256|ARBA:ARBA00035286};
DE AltName: Full=39S ribosomal protein L22, mitochondrial {ECO:0000256|ARBA:ARBA00035506};
GN Name=MRPL22 {ECO:0000313|VGNC:VGNC:55457};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000015754.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000015754.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000015754.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000015754.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000015754.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL22 family.
CC {ECO:0000256|ARBA:ARBA00009451, ECO:0000256|RuleBase:RU004005}.
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DR AlphaFoldDB; F6QBM1; -.
DR STRING; 9796.ENSECAP00000015754; -.
DR PaxDb; 9796-ENSECAP00000015754; -.
DR Ensembl; ENSECAT00000019260.4; ENSECAP00000015754.3; ENSECAG00000018172.4.
DR VGNC; VGNC:55457; MRPL22.
DR GeneTree; ENSGT00390000002110; -.
DR HOGENOM; CLU_100005_1_0_1; -.
DR InParanoid; F6QBM1; -.
DR TreeFam; TF315111; -.
DR Proteomes; UP000002281; Chromosome 14.
DR Bgee; ENSECAG00000018172; Expressed in gluteus medius and 23 other cell types or tissues.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd00336; Ribosomal_L22; 1.
DR Gene3D; 3.90.470.10; Ribosomal protein L22/L17; 1.
DR InterPro; IPR001063; Ribosomal_uL22.
DR InterPro; IPR047867; Ribosomal_uL22_bac/org-type.
DR InterPro; IPR036394; Ribosomal_uL22_sf.
DR PANTHER; PTHR13501:SF8; 39S RIBOSOMAL PROTEIN L22, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13501; CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED; 1.
DR Pfam; PF00237; Ribosomal_L22; 1.
DR SUPFAM; SSF54843; Ribosomal protein L22; 1.
PE 3: Inferred from homology;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU004005};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW ECO:0000256|RuleBase:RU004005}.
SQ SEQUENCE 217 AA; 25151 MW; C4791E1C1B925F85 CRC64;
MAAAILERLG ALWMQNLRGK LTLGLLSSHS VPQSQIHTSA SLDISRKWEK KNKIVYPPQL
PGEPRRPAFF FLLISKEIYH CRRQIKYSKD KMWYLAKLIR GMSIDQALAQ LEFSDKKGAQ
IIKEVLLEAQ EMAVRDHNVE FRSNLYIAES TSGRGQYLKR IRYHGRGHFG IMEKVYCHYF
VKLVEGPPPP HEAPKTALTH AKEYIQELRN RTIIHTL
//
