ID F6R7Y9_MONDO Unreviewed; 487 AA.
AC F6R7Y9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=ADP dependent glucokinase {ECO:0000313|Ensembl:ENSMODP00000012448.2};
GN Name=ADPGK {ECO:0000313|Ensembl:ENSMODP00000012448.2};
OS Monodelphis domestica (Gray short-tailed opossum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000012448.2, ECO:0000313|Proteomes:UP000002280};
RN [1] {ECO:0000313|Ensembl:ENSMODP00000012448.2, ECO:0000313|Proteomes:UP000002280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17495919; DOI=10.1038/nature05805;
RA Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S.,
RA Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M.,
RA Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.,
RA Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E.,
RA Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A.,
RA Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S.,
RA Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E.,
RA Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K.,
RA VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C.,
RA Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT "Genome of the marsupial Monodelphis domestica reveals innovation in non-
RT coding sequences.";
RL Nature 447:167-177(2007).
RN [2] {ECO:0000313|Ensembl:ENSMODP00000012448.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_001365190.1; XM_001365153.4.
DR AlphaFoldDB; F6R7Y9; -.
DR STRING; 13616.ENSMODP00000012448; -.
DR Ensembl; ENSMODT00000012674.3; ENSMODP00000012448.2; ENSMODG00000009941.3.
DR GeneID; 100016323; -.
DR KEGG; mdo:100016323; -.
DR CTD; 83440; -.
DR eggNOG; KOG4184; Eukaryota.
DR GeneTree; ENSGT00390000017953; -.
DR HOGENOM; CLU_032362_0_0_1; -.
DR InParanoid; F6R7Y9; -.
DR OMA; MWRKASA; -.
DR OrthoDB; 51859at2759; -.
DR TreeFam; TF313401; -.
DR Proteomes; UP000002280; Chromosome 1.
DR Bgee; ENSMODG00000009941; Expressed in forelimb bud and 17 other cell types or tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0043843; F:ADP-specific glucokinase activity; IBA:GO_Central.
DR GO; GO:0006006; P:glucose metabolic process; IBA:GO_Central.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR CDD; cd01938; ADPGK_ADPPFK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR007666; ADP_PFK/GK.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR21208; ADP-DEPENDENT GLUCOKINASE; 1.
DR PANTHER; PTHR21208:SF0; ADP-DEPENDENT GLUCOKINASE; 1.
DR Pfam; PF04587; ADP_PFK_GK; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS51255; ADPK; 1.
PE 4: Predicted;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000002280};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..487
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023871570"
SQ SEQUENCE 487 AA; 52474 MW; E82E0314613F759D CRC64;
MAVWNGPAFA GFLAVAVGSF LLLQPELPGS ALRALWGSLN GGASAEGRLA AAWEALIVRP
ERSWNRVAVG VNACVDVVLS GVKLLQALGL SPGDGEDHSV LHSRKDLEEA FIHFMGKGAA
AERFFSDGES FHNISQIASE LPGAQHYVGG NAALIGQKLA ANSDLKVLLC GPVGPKLHQL
LDDNIVVPPE SMQEVDEFHL ILEYQAGEQW GPLTAPNANR FIFSHDLSNG AMNMLEVFVS
SLEEFQPDLV VLSGLHMMEG QTKEIQKKRL QEAVISISDI PTDVPIHLEL ASMTDRELMS
SIMHQVFPLV NSLGLNEQEL LFLSQSASGP HSSLPAWSGV PDVGVVSDIL FWILKEQGRS
KERASDLTRI HFHTLAYHIL ATVDGHWGNQ LASVAAGARV AGTQACATET IDSGRVSLKA
PLEFVTSHSE AGSRIAVNPD EPVAQWRREG VSFHFTPVLV CKDPIRTVGL GDAISAEGLF
YSEAYPH
//
