ID F6UVU7_CIOIN Unreviewed; 457 AA.
AC F6UVU7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Src kinase-associated phosphoprotein 2-like {ECO:0000313|Ensembl:ENSCINP00000026843.2};
GN Name=LOC100175993 {ECO:0000313|Ensembl:ENSCINP00000026843.2};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000026843.2, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000026843.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; EAAA01002536; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F6UVU7; -.
DR STRING; 7719.ENSCINP00000026843; -.
DR Ensembl; ENSCINT00000027089.2; ENSCINP00000026843.2; ENSCING00000014974.2.
DR GeneTree; ENSGT00390000017856; -.
DR HOGENOM; CLU_599284_0_0_1; -.
DR InParanoid; F6UVU7; -.
DR Proteomes; UP000008144; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR037781; SKAP_fam.
DR PANTHER; PTHR15129:SF0; PH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15129; SRC-ASSOCIATED ADAPTOR PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008144}.
FT DOMAIN 124..227
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 260..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..356
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 50187 MW; 8AA12BED4CDC2202 CRC64;
MESGALREAT SQLSAVLTFL LKLKLDKKLT SEKDTLIESL KKTLEKCRKI ASTEEGEVYN
DVVTNDSEVY NDVEGKEVEE TTYNDTAQPN DVYTDTVADQ QDEYTDLEAP TREIAPIPCE
ELTTATMCNH LHLKSKSMLM GAWQKRWCVL DKNVFYMYDS SKDKKQKEAF SVVGFSFQVR
DDITKEAKRK ERCFELKNDK LNKVYCFCAS DKESLQKWKK VLSAATRGLS ASHCSTTSME
TVTPTHGKKS FFNIISSLGS KNSKSSASIS EVGDDSVYDD TGPGETYDDL DILPPNGDYT
DTGASETYMD TAVNNDDVYE DTQPPEENYE DLATNPAPDP TKRNLPLPPP SLGPKPGKSL
GSPLLPPRDR SPSRSSLTPT GESPGWSSVP KLPPRSPTGG AHIEESGSAS GAFNRKELPV
PDKSRNLPPV PGNKHEMKTT PLPPSPIPSP PGVIDDG
//
