ID F6Y927_ORNAN Unreviewed; 922 AA.
AC F6Y927;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=MORC family CW-type zinc finger 3 {ECO:0000313|Ensembl:ENSOANP00000015498.2};
GN Name=MORC3 {ECO:0000313|Ensembl:ENSOANP00000015498.2};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000015498.2, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000015498.2, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000015498.2,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000015498.2}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000015498.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6Y927; -.
DR STRING; 9258.ENSOANP00000015498; -.
DR Ensembl; ENSOANT00000015501.2; ENSOANP00000015498.2; ENSOANG00000009766.3.
DR eggNOG; KOG1845; Eukaryota.
DR GeneTree; ENSGT00940000160495; -.
DR HOGENOM; CLU_011516_2_0_1; -.
DR TreeFam; TF329118; -.
DR Proteomes; UP000002279; Chromosome 17.
DR Bgee; ENSOANG00000009766; Expressed in testis and 8 other cell types or tissues.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16931; HATPase_MORC-like; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR045261; MORC_ATPase.
DR InterPro; IPR041006; Morc_S5.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR23336:SF17; MORC FAMILY CW-TYPE ZINC FINGER PROTEIN 3; 1.
DR PANTHER; PTHR23336; ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF17942; Morc6_S5; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00454}.
FT DOMAIN 395..445
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT REGION 508..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 673..714
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 748..775
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 805..846
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 508..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..625
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 922 AA; 103946 MW; 5F66FA246BB7098F CRC64;
PVLPPPLTLC PKFLHTNSTS HTWPFSAVAE LIDNAYDPDV NAKQIWIDKT VINDNICLTF
TDNGNGMTSE KLHKMLSFGF SDKVTVNGRV PVGLYGNGFK SGSMRLGRDA IVFTKNGESL
SVGLLSQTYL ATIKAEHVVV PIVVFNRHTA ESKANLRAIL AHSLFSTEQK LLAELDAIMG
KKGTRIIIWN LRRDKNEATE FDFDKDKYDI RIPEEIDETT GKKGYKKQER MDQIVPESDY
SLRAYCSILY LKPRMQIILR GQKVKTQLVS KSLAYIEQDI YRPKFLGKTV RITFGFNCRN
KDHYGIMMYH SNRLIKAYER VGCQLKANNM GVGVVGIIEC NFLKPTHNKQ DFDYTNEYRL
TITALGEKLS DYWNEMKVKK NEEHSQSLPV EDIQKRPDQL WVQCDSCLKW RKLPDGIDCL
PDKWYCSLNP DPQFRSCSVP EEPEDEDLVH PTYEKTYKKN SFVFQISTEV LYGESSVSSS
KDFTTPVKEN NSRLQLAEMG KTIITRSVNS ANNRQSSPPS DADCNSIKRR LPVSTPSSAK
IPRLNGQAPD KSFEVEDDDE DVIILEESST PKPTSDGGVT IIKIEPGHPE QSSPRKESAT
SKSTREDTGS GPRCEQGTAA TQTEIPNIIV KKEEAVEDEI DSRNGAVMQQ PRREAETSKE
AIARDFGDAG TQVVELRNQL LVACQEKENY RQQCEMLTEQ VQGLEQKILE MNDKYVKKEI
CHQSTEIDIE LLGEMPAVVP GSSASQGADQ LAGLYEQALK EVEKLKEQCD TLRNLKAECS
KCSNPENKTE VDVMAFQLDD VFRQLDKCSI ERDQYKSEVE LLEVEKTQMG VQCEELKSEV
EQLKASVPQV PSTENSTTGN VEDSVKFSDG ESFKLRSLRV NVGQLLATMM PDLDLQQVNY
DVDVVDEILG QVVEQMHEIS ST
//
