ID F6YBZ9_XENTR Unreviewed; 1172 AA.
AC F6YBZ9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=BAI1-associated protein 3 {ECO:0000313|Ensembl:ENSXETP00000046644, ECO:0000313|RefSeq:XP_002938461.3};
GN Name=baiap3 {ECO:0000313|Ensembl:ENSXETP00000046644,
GN ECO:0000313|RefSeq:XP_002938461.3, ECO:0000313|RefSeq:XP_031749080.1,
GN ECO:0000313|Xenbase:XB-GENE-956301};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000046644};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000046644}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000046644};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000046644}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_002938461.3, ECO:0000313|RefSeq:XP_031749080.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_002938461.3,
RC ECO:0000313|RefSeq:XP_031749080.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_002938461.3,
RC ECO:0000313|RefSeq:XP_031749080.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the unc-13 family.
CC {ECO:0000256|ARBA:ARBA00005823}.
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DR RefSeq; XP_002938461.3; XM_002938415.5.
DR RefSeq; XP_031749080.1; XM_031893220.1.
DR Ensembl; ENSXETT00000046644; ENSXETP00000046644; ENSXETG00000021585.
DR KEGG; xtr:100492796; -.
DR AGR; Xenbase:XB-GENE-956301; -.
DR Xenbase; XB-GENE-956301; baiap3.
DR eggNOG; KOG1328; Eukaryota.
DR HOGENOM; CLU_003295_2_0_1; -.
DR OMA; WLAEAMN; -.
DR TreeFam; TF315526; -.
DR Proteomes; UP000008143; Chromosome 9.
DR Bgee; ENSXETG00000021585; Expressed in brain and 8 other cell types or tissues.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR CDD; cd08676; C2A_Munc13-like; 1.
DR CDD; cd04009; C2B_Munc13-like; 1.
DR Gene3D; 1.10.357.50; -; 1.
DR Gene3D; 1.20.58.1100; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR010439; MUN_dom.
DR InterPro; IPR014770; Munc13_1.
DR InterPro; IPR014772; Munc13_dom-2.
DR PANTHER; PTHR45999:SF1; BAI1-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR45999; UNC-13-4A, ISOFORM B; 1.
DR Pfam; PF00168; C2; 3.
DR Pfam; PF06292; MUN; 1.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS51258; MHD1; 1.
DR PROSITE; PS51259; MHD2; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 142..306
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 638..759
FT /note="MHD1"
FT /evidence="ECO:0000259|PROSITE:PS51258"
FT DOMAIN 873..981
FT /note="MHD2"
FT /evidence="ECO:0000259|PROSITE:PS51259"
FT DOMAIN 996..1121
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 22..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1172 AA; 135200 MW; E13F07A4447B3C44 CRC64;
MSTLLEIKSS VLRQVQNRQS FRRRAEMESS NSTQETCKVP SADREGTGDF FDRMRSVLQK
QENMQRYWRT EGVLNNSIPP PPENVGEHKV LEKLLLSKRE IEMLYEEILY TLVYTAGIVS
SEHIGSEEEL FHYLQKVFGV SKSDHDPILQ HVKESKAPVF ALKVTVVQGR NLLAKDPNGF
SDPYCMLGIM IMQSSKETEE KKERKFSFRK KKDKIEKRSS IREVLPAKYI QVTEVKSNTL
NPVWNENFLF EIDDIFSDQL HLDIWDHDDD VSVAEACKKL NEVSGFKGMG RYFKQIVKSA
RANGTTGSAE DNADDFLGCL NISINEIPVG GLDKWFKLEP RTSSSRVQGD CHLIIKLITN
QRDTVLSKKA SGSVIHEMLL NQLLQYEHKQ TEVESWNWKG ELSKHAFTIL SHHSMQTDLS
SLQQAVIKWQ AFSKHHQIQA MDYSFLLGLL KHIEEQWDPT MCQREQEQSL AESFTLFTEY
CLLLLKKLRD NFPVLNTTVI NRLEFMLRCL SQIQNMQAFR MVCPFHNELH LEIAAIIKKG
TLEWYEKTHA SLRPEEKNTV EQLRCLARLT DAVHEDIEKS QNVYNKLFVS IVKVDYFSIT
YRQLEKLVAD EVSAAMGALK GTEPESPQIT HAIGEALYEL YITLSELRKF RDYLPLKDNK
SLALSGFHEL FKVSIHTWLI TIHEKTCERI QRAVELDKLE YVDSLSKHSS SAVDVTICFS
QIKEFWAQLA WPDSAEAFVF LTQLSDDICK AAIYYSEAIR RKVDKSHQAS VGQAVITEQL
CIVLNNIEHI RKFMGNILRD LDWKPLEMAV ELSPGTDGKP QVQKALNTQL QNIDIDMQRE
AKNMISHLTE KMIGDIKKYI QHISLSPDSI QNDEAVSPLM KYLDDKLIIL NETLVKENLH
RVLDALWWLL LKFIIDAVDS NRGVSVEFYG RFYYTLEALV DFFHAEGQGL ALETLRNGDY
RFLEEELRLN KCSTSELIEK YYLDNTKEQR SSEQSKYGRL SVKCYYESSE QKLYVEVLHA
ADLIALDANG LSDPFVIIEL CPHHIFPLVK CQRTQVKPKT LHPVYDELFY FSVSSEQCRR
KSACILFTVM DHDWLSTNDF AGEAVLPMNV IYGLNRPHIT GGVKNVQPTV LKLTRPKANV
KSILKMLDGR MDKEAQEFVK KLREMEKYME DD
//
