ID F7AFY6_ORNAN Unreviewed; 1052 AA.
AC F7AFY6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Cadherin like and PC-esterase domain containing 1 {ECO:0000313|Ensembl:ENSOANP00000008993.2};
GN Name=CPED1 {ECO:0000313|Ensembl:ENSOANP00000008993.2};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000008993.2, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000008993.2, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000008993.2,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000008993.2}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000008993.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7AFY6; -.
DR STRING; 9258.ENSOANP00000008993; -.
DR Ensembl; ENSOANT00000008995.3; ENSOANP00000008993.2; ENSOANG00000005654.3.
DR eggNOG; ENOG502QQAY; Eukaryota.
DR GeneTree; ENSGT00390000015216; -.
DR HOGENOM; CLU_011328_0_0_1; -.
DR InParanoid; F7AFY6; -.
DR OMA; HRYTVVI; -.
DR OrthoDB; 1097907at2759; -.
DR TreeFam; TF332741; -.
DR Proteomes; UP000002279; Chromosome 10.
DR Bgee; ENSOANG00000005654; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR025883; Cadherin-like_b_sandwich.
DR PANTHER; PTHR14776; CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR14776:SF1; CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12733; Cadherin-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 608..691
FT /note="Cadherin-like beta sandwich"
FT /evidence="ECO:0000259|Pfam:PF12733"
SQ SEQUENCE 1052 AA; 120772 MW; 7AD2046333539376 CRC64;
MIRRQIFLCC RCVCPRPFFL GIVVAVCLFY QTLTLIGSRR FMSAVKGLSP NKLTEASQGR
VKDTFSRATV CFFPSGDPQA IEKIEESVAK HFGSHGRRAV LHTPPSHCKM EMELYQRILT
RHGYLVVPSE GKRRSAVGLG DLNPGDSHSW DLLICLSPYK ANEEPCISKE DFKHLGVHQK
VNMLPEIQHQ LCRREGLCQL TKRFPELHLP ITPSVCLDQP VQPRRNSADR FWKREVSRET
HLVHRWNPWN WPSDPHPNQT PVPAVPKEPF KGRGLSVIIK AYVLVTSLTP LRAFIHSTGT
VWNPPKKKCF SIKLQTFFET FLRVSSPLQA FDNMKEAISK LLLVAEVSSE APARGPKTFA
RCRLCFQLLT FDIDYSSSLD PVVLEVHEDF DFPVDDSLDV EDQITKKFLV EDTFSFLLAK
ESSLSIYSEA FWRTFRPGTV KDETHQKEYN QCLPLEEIHS MMTFAQELKN LGQFQLLLPS
KAPRIQTLLH TINYLTEPTQ KPSSVPRRYR LLLNLLEQFQ LMNQKTPVHP FAWKSKTSVR
NSFKVVLKQP SLRNSFSEEK PGKHRMPFDV PEKQKVPNFF NETTEVHCSN DKDTLSHIKH
IFTNPHLDLN PEFNPKIREY SCEVPFDVVM VKIGAESSNC RCKVHLDERT GPSFANYPLG
LGVNKITLLV VDESQVNGDI LSSYRITIYR EDRPSLPVFD DYVACGFVQD CGLLIHSDKP
CSLQQLSSDY IAAISQPDLR TCESGDARGQ WIVPCLSCSD NRTCDWREIT WQPQNCQFGV
LSKVQLQRCL DRRKVLFIGD STNRGIMYYL IERVNETLQE WQKLHGTKTY PNINDGKTLI
SYSYYPQFWI DVTQRPTFEK ALEQLLQRSS PLENTDQTVL VVGGVQWLNS NHLQIIRKVL
KRENLLNILV VIKTIGMGFH LPVDGVHSLS QSEVKNLWKE NLFILDSAKR YGFEVVDTFQ
ITMGRHKEFL QGKCGCHFHE VVKSKASTDH RLIKMKLSRH HGVGKYFSNQ SKLSRLQDSA
TNVQSPYRVR GPINRVYSEI LLSRICSSRR TT
//
