ID F7AQE8_MOUSE Unreviewed; 251 AA.
AC F7AQE8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Chitinase-like 5 {ECO:0000313|Ensembl:ENSMUSP00000065043.5};
DE Flags: Fragment;
GN Name=Chil5 {ECO:0000313|Ensembl:ENSMUSP00000065043.5,
GN ECO:0000313|MGI:MGI:2676649};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000065043.5, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000065043.5, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000065043.5,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000065043.5}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000065043.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7AQE8; -.
DR SMR; F7AQE8; -.
DR Ensembl; ENSMUST00000066537.10; ENSMUSP00000065043.5; ENSMUSG00000043873.12.
DR AGR; MGI:2676649; -.
DR MGI; MGI:2676649; Chil5.
DR VEuPathDB; HostDB:ENSMUSG00000043873; -.
DR GeneTree; ENSGT00940000154557; -.
DR ChiTaRS; Chil5; mouse.
DR Proteomes; UP000000589; Chromosome 3.
DR Bgee; ENSMUSG00000043873; Expressed in granulocyte and 23 other cell types or tissues.
DR ExpressionAtlas; F7AQE8; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; ISO:MGI.
DR GO; GO:0008061; F:chitin binding; IBA:GO_Central.
DR GO; GO:0004568; F:chitinase activity; IBA:GO_Central.
DR GO; GO:0019900; F:kinase binding; ISO:MGI.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006032; P:chitin catabolic process; ISO:MGI.
DR GO; GO:0032722; P:positive regulation of chemokine production; ISO:MGI.
DR GO; GO:0002532; P:production of molecular mediator involved in inflammatory response; ISO:MGI.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11177:SF188; ACIDIC MAMMALIAN CHITINASE; 1.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 1..210
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000065043.5"
SQ SEQUENCE 251 AA; 27780 MW; 91B5B2B37E0DB434 CRC64;
GRDFGPAPFS AMVSTPHNQQ TFINSAIKFL RQYGFDGLNL DWQFPGSRGS PSRDKHLFTV
LVQDYIMTYW NENGAAPEKL IVGFPAYGQT FTLSDPSNNG ISAPTASAGT LGPYTEESGT
WAYYEICSFL NDGATEAWDS AQEVPYAYQG NKWVGYDNVK SFRIKAEWLK QNNLGGAMLW
TLDMDDFTGS FCNQGQFPLT STLKNALLVY STSCMASVSD LQQVNAPLYS GNRNWKRGSK
AMDSVSPVPR E
//
