ID F7AYA6_HORSE Unreviewed; 401 AA.
AC F7AYA6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 4.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Protein phosphatase 1 regulatory subunit 7 {ECO:0000313|Ensembl:ENSECAP00000014938.4};
GN Name=PPP1R7 {ECO:0000313|Ensembl:ENSECAP00000014938.4,
GN ECO:0000313|VGNC:VGNC:52421};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000014938.4, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000014938.4, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000014938.4,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000014938.4}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000014938.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7AYA6; -.
DR STRING; 9796.ENSECAP00000014938; -.
DR PaxDb; 9796-ENSECAP00000014938; -.
DR Ensembl; ENSECAT00000018319.4; ENSECAP00000014938.4; ENSECAG00000017246.4.
DR VGNC; VGNC:52421; PPP1R7.
DR GeneTree; ENSGT00940000158551; -.
DR HOGENOM; CLU_044236_1_1_1; -.
DR InParanoid; F7AYA6; -.
DR OMA; EVWASYN; -.
DR OrthoDB; 8274at2759; -.
DR TreeFam; TF105538; -.
DR Proteomes; UP000002281; Chromosome 6.
DR Bgee; ENSECAG00000017246; Expressed in cerebellum and 23 other cell types or tissues.
DR ExpressionAtlas; F7AYA6; baseline.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR Pfam; PF12799; LRR_4; 3.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00365; LRR_SD22; 10.
DR SMART; SM00369; LRR_TYP; 7.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 9.
PE 1: Evidence at protein level;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F7AYA6};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 401 AA; 45568 MW; C965AEBBC3DE4D73 CRC64;
MAEERGGGQQ QSQEMMEVDR RVESEESGDE EGKKQSSGLV ADLSEHSLKD GEEPGDEDPE
EGQELPVDME TINLDKDAED VDLNHYRIGK IEGFEVLKKV KTLCLRQNLI KCIENLEELQ
SLRELDLYDN QIKKIENLEA LTELEILDIS FNLLRNIEGI DKLTRLKKLF LVNNKINKIE
NISNLRQLQM LELGSNRIRA IENIDTLTNL ESLFLGKNKI TKLQNLDALT NLTVLSMQSN
RLTKIEGLQN LVNLRELYLS HNGIEVIEGL ENNNKLTMLD VASNRIKKIE NISHLTELQE
FWMNDNLLES WSDLDELKGA KNLETVYLER NPLQKDPQYR RKIMLALPTV RQIDATFVSR
VDTRQPPAGW GALPSPGLVS PTQYLPAVPM LVLGVGTQMG S
//
