ID F7BGV9_HORSE Unreviewed; 503 AA.
AC F7BGV9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 4.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN Name=LOC100053055 {ECO:0000313|Ensembl:ENSECAP00000011746.4};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000011746.4, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000011746.4, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000011746.4,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000011746.4}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000011746.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7BGV9; -.
DR STRING; 9796.ENSECAP00000011746; -.
DR PaxDb; 9796-ENSECAP00000011746; -.
DR Ensembl; ENSECAT00000014684.4; ENSECAP00000011746.4; ENSECAG00000035495.3.
DR GeneTree; ENSGT01100000263478; -.
DR InParanoid; F7BGV9; -.
DR TreeFam; TF336644; -.
DR Proteomes; UP000002281; Chromosome 10.
DR Bgee; ENSECAG00000035495; Expressed in leukocyte and 13 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11738:SF88; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11738; MHC CLASS I NK CELL RECEPTOR; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13895; Ig_2; 2.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..503
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040402080"
FT DOMAIN 230..407
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 439..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 503 AA; 54757 MW; CBCD02AD2CDA878A CRC64;
MEGRARTPVL TALLCLGLCQ DLWNQVQAGV TPKPSIWADP GPVVTWGSPV TIWCQGSLQA
DVYHLYRGRV SKPVYIEAPQ DSSNKTSFFI ESMSTHTAGL YQCAYHIRRN GWSERSDPLR
LVVTGAYSAP SLSAHPGPVV ASGGNVSLWC SSEVTSGTFH LLKEGGANSS QQMEPRIHHG
RWQALFPVGP VNTSHGGTYR CYGSPSSYPY AWSQPSDPLH LEVTGVYREP SLSAQPGSLV
LSGDNLTLQC RSEADFDRFA LTRDEGLTPP QHLHEQHSPD FPLGHVSHTH GGQYRCYGGY
NLSHVWSAPS APLDILIAGM YEKPSLSAQP GPSVSWGENV TLRCRSEIWF DTFHLSKEGS
PAPPQHLRLQ DTAAPFQANF TIGPVTSDHE GTYRCYGSNS TSPHLLSLPS DLLELRVSGE
EPQSCPLCPH GQFRVPSPGE IWAGMGVRGS QKASQPEGNL ASQRDGKSQS KSQPTSCSCP
SSSPSLRSRD ICGEWRQLER TQG
//
