ID F7BL63_CIOIN Unreviewed; 588 AA.
AC F7BL63;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Uncharacterized LOC100182710 {ECO:0000313|Ensembl:ENSCINP00000000761.3};
GN Name=LOC100182710 {ECO:0000313|Ensembl:ENSCINP00000000761.3};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000000761.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000000761.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7BL63; -.
DR Ensembl; ENSCINT00000000761.3; ENSCINP00000000761.3; ENSCING00000000417.3.
DR GeneTree; ENSGT00940000173974; -.
DR HOGENOM; CLU_463762_0_0_1; -.
DR InParanoid; F7BL63; -.
DR OMA; YEEPWDK; -.
DR TreeFam; TF325799; -.
DR Proteomes; UP000008144; Unplaced.
DR GO; GO:0001784; F:phosphotyrosine residue binding; IBA:GO_Central.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR15127; HEAVYWEIGHT, ISOFORM A; 1.
DR PANTHER; PTHR15127:SF32; HEAVYWEIGHT, ISOFORM A; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 488..583
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 24..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..200
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..441
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 588 AA; 66779 MW; 9ACF79DD1E9D1A06 CRC64;
MNRKWNLFKK NKINKTDSHG TTLVDEEIQF QPTTDNNSQW KGNSLKPSTT KPTRGHQSGE
EGHVTKENEY ENSEVARGVV RSRGELMPLD TRSVVPRTSP TITKKLIKPG NKNATMLIPS
SDPSSSISIS DEYVEPFDSV KRDNKAMEGY IEPYEAQQMY QELTQNSDAA KSSKSKIYDE
PWDKSKQKDK DYEEPWDKTN TLPYKDNNNI NHGSSDSLSA LRGKQKMVFV PSQQRSPSSS
PMLDRRLIRP PDTNTRRQER VVDHRLIKVE PSFDEIRRSN SRNTGSSGTN SPISKHNSPN
HSPVNTLIVT NEVVDLRRAS SPLVQPMNIS LYRLSKAKSR SLDIRSKQGL SALRGDGGIP
KSSSDDHLVQ SAQVTVPTNK SLDGVSEYEE PWDTETTLKH GNPHISHSRS RSYEISSVPQ
LNRHSKSHSF DNQDPGDDYE HPWDKPSIPK VHLESMQRFQ HRQLELHPSE AIADKDFDPL
LPLTKQGWYH GAITRDEANM RLSREVPGSY LVRNSESTAN NYSLSLRTRS TTIHMVISST
RDGFWILGEF SAPFHSVPEM IAFYSTHRLK INDTQNISLK YPITEDYL
//
