ID F7C302_ORNAN Unreviewed; 520 AA.
AC F7C302;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Gypsy retrotransposon integrase-like protein 1 {ECO:0000256|ARBA:ARBA00039658};
GN Name=GIN1 {ECO:0000313|Ensembl:ENSOANP00000008669.2};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000008669.2, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000008669.2, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000008669.2,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000008669.2}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000008669.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007669983.1; XM_007671793.1.
DR AlphaFoldDB; F7C302; -.
DR STRING; 9258.ENSOANP00000008669; -.
DR Ensembl; ENSOANT00000008671.4; ENSOANP00000008669.2; ENSOANG00000005453.4.
DR GeneID; 103171138; -.
DR KEGG; oaa:103171138; -.
DR CTD; 54826; -.
DR eggNOG; KOG0017; Eukaryota.
DR GeneTree; ENSGT00940000160670; -.
DR HOGENOM; CLU_040181_0_0_1; -.
DR InParanoid; F7C302; -.
DR OMA; YPNNWDD; -.
DR OrthoDB; 1012429at2759; -.
DR TreeFam; TF352301; -.
DR Proteomes; UP000002279; Chromosome 10.
DR Bgee; ENSOANG00000005453; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47266; ENDONUCLEASE-RELATED; 1.
DR PANTHER; PTHR47266:SF28; GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT DOMAIN 128..286
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 322..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..500
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 58548 MW; D9FD6916AC6C98FD CRC64;
MVRSGKNGSL HLKQIAYYKR TGEYHPTTLP SERSGIRRAA KKFDFKEKRL FYIGKDRKQN
RLVIVSEEEK RKVLRECHEN DTGAHHGISR TLTLVESSYY WTSVTNDVKQ WVSACQHCQV
SKQPPLLKVE DPWAIVAVDL MGPFLSSSRS QNQYIMMMTD LFTKWVVISP LRDISAPEIS
KAIANAFFSY GPPQKIVMDQ GEEFIYQINT ELCGLFGTKL IVTAHPSPSD DGNERMLGVM
KTFLPQYCTE HSSDWDAHLS AVAFAFNSTP LGSTKNTPYF QMFNRNPHVP ETPEVLREVE
GVHVCVFAKI LDAIKEADRA AETKIPSRQM ESGIPDEEPS RSKIAPKRKA KQLNPFHLKV
GHEVVRQRKN RWKDGRFHSE WVGPCVIDYV TDGGCAVLRD ATGSRLKRPI KMSHLKPYIR
TSGDQGSHHL LQGPAAVDHD YIGTSEITVG SRHPGVPPKD TSPRASDDES PTSGEDHELS
ESKNPDGSPL PEDHRMRPAN RTPGKSTFYR LLDASSQVTE
//
