ID F7CG23_ORNAN Unreviewed; 203 AA.
AC F7CG23;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 3.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Translation machinery-associated protein 16 {ECO:0000256|ARBA:ARBA00020047};
GN Name=TMA16 {ECO:0000313|Ensembl:ENSOANP00000013070.3};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000013070.3, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000013070.3, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000013070.3,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000013070.3}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000013070.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit in
CC the nucleus. {ECO:0000256|ARBA:ARBA00034079}.
CC -!- SUBUNIT: Associates with pre-60S ribosomal particles.
CC {ECO:0000256|ARBA:ARBA00034132}.
CC -!- SIMILARITY: Belongs to the TMA16 family.
CC {ECO:0000256|ARBA:ARBA00034127}.
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DR AlphaFoldDB; F7CG23; -.
DR STRING; 9258.ENSOANP00000013070; -.
DR Ensembl; ENSOANT00000013072.3; ENSOANP00000013070.3; ENSOANG00000008227.3.
DR eggNOG; ENOG502RXYZ; Eukaryota.
DR GeneTree; ENSGT00390000004179; -.
DR HOGENOM; CLU_105581_1_0_1; -.
DR InParanoid; F7CG23; -.
DR OMA; SWFLGQI; -.
DR OrthoDB; 5394776at2759; -.
DR TreeFam; TF324892; -.
DR Proteomes; UP000002279; Chromosome 12.
DR Bgee; ENSOANG00000008227; Expressed in fibroblast and 8 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:1990275; F:preribosome binding; IEA:Ensembl.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:Ensembl.
DR Gene3D; 1.20.1440.170; Translation machinery-associated protein 16-like; 1.
DR InterPro; IPR021346; Tma16.
DR InterPro; IPR038356; Tma16_sf.
DR PANTHER; PTHR13349:SF2; TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16; 1.
DR PANTHER; PTHR13349; UNCHARACTERIZED; 1.
DR Pfam; PF11176; Tma16; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002279}.
SQ SEQUENCE 203 AA; 23845 MW; 5EDC0C3977FEBACC CRC64;
MPKAPKGKGV GHEKKVIHPY SRKAAQLTRE AHKQDKREKL KNDKALRLNI IGEKLQWFQS
HLDPSKAEYT KKEACELVES YILRFSSELE QIELRNSIKG RRGRQHCARE ATIRQTMERE
RRLYEGYGLE IPDIVNAKHL KTFREWDCDL QKLPNIKMRK FCASDAVSKR KKNVELKEEP
CGEKVEDINM LDEMEEENSA HED
//
