ID F7E6F2_XENTR Unreviewed; 300 AA.
AC F7E6F2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 3.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Mitochondrial GTPase 1 {ECO:0000256|PIRNR:PIRNR006230};
GN Name=mtg1 {ECO:0000313|Ensembl:ENSXETP00000047909};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000047909};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000047909}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000047909};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000047909}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
CC -!- FUNCTION: Plays a role in the regulation of the mitochondrial ribosome
CC assembly and of translational activity. Displays mitochondrial GTPase
CC activity. {ECO:0000256|PIRNR:PIRNR006230}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|PIRNR:PIRNR006230}; Peripheral membrane protein
CC {ECO:0000256|PIRNR:PIRNR006230}.
CC -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1
CC subfamily. {ECO:0000256|PIRNR:PIRNR006230}.
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DR AlphaFoldDB; F7E6F2; -.
DR Ensembl; ENSXETT00000047909; ENSXETP00000047909; ENSXETG00000022149.
DR AGR; Xenbase:XB-GENE-957647; -.
DR Xenbase; XB-GENE-957647; mtg1.
DR Bgee; ENSXETG00000022149; Expressed in heart and 10 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01856; YlqF; 1.
DR Gene3D; 1.10.1580.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR InterPro; IPR016478; GTPase_MTG1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45782; MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1; 1.
DR PANTHER; PTHR45782:SF4; MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR PIRSF; PIRSF006230; MG442; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|PIRNR:PIRNR006230, ECO:0000256|PIRSR:PIRSR006230-
KW 1}; Mitochondrion {ECO:0000256|PIRNR:PIRNR006230};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR006230,
KW ECO:0000256|PIRSR:PIRSR006230-1}.
FT DOMAIN 126..225
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
FT BINDING 63..66
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
FT BINDING 133..138
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
FT BINDING 185
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
SQ SEQUENCE 300 AA; 33618 MW; 3F478E6B42F4A7C1 CRC64;
MRTSFDFGER EVAHWFPGHM AKGLKQMKTK LKNLDCIVEV HDARISFIIS DSLGMKPHLL
ILNKMDLADL TQKKRILAQL KQQGVGNVIF TDCVKDQNIK HVVPVISELV GCSQRFHREE
NTETCIMVIG VPNVGKSSLI NALRRMHLRK GKASRVGAEP GITRSVLTKI QVSESPLIFL
FDTPGVLSPR IESVETGMKL ALCGTILDHL VGEDIMADYL LYILNQQMQH RYVEHYGLEK
PCADIETLLK RIALKLGKTQ KVKAITGVGD VNITVPNYNA AAYDFIRTFR RGQLGVVMLD
//
