ID F7E7W2_XENTR Unreviewed; 568 AA.
AC F7E7W2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Nucleolar protein 56 {ECO:0000256|ARBA:ARBA00040742};
DE AltName: Full=Nucleolar protein 5A {ECO:0000256|ARBA:ARBA00041388};
GN Name=nop56 {ECO:0000313|Ensembl:ENSXETP00000032695};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000032695};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000032695}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000032695};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000032695}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
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DR AlphaFoldDB; F7E7W2; -.
DR Ensembl; ENSXETT00000032695; ENSXETP00000032695; ENSXETG00000014962.
DR AGR; Xenbase:XB-GENE-5879910; -.
DR Xenbase; XB-GENE-5879910; nop56.
DR HOGENOM; CLU_015495_4_1_1; -.
DR InParanoid; F7E7W2; -.
DR Reactome; R-XTR-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Bgee; ENSXETG00000014962; Expressed in neurula embryo and 18 other cell types or tissues.
DR ExpressionAtlas; F7E7W2; differential.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF0; NUCLEOLAR PROTEIN 56; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 324..442
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 468..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..568
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 63327 MW; 55946CFD61F3F1D7 CRC64;
MCLPPRCCSC PSPPCVCPPG AAPAPHPHVF APQVLLHVLF EHAAGYALFV VKEVEEIGLL
IPQVEESLLN VGKFNNIVKL AAFSPFKSAQ SALENVNAIS EGVLHEDLKL LLETNMPAKK
KKALLGVGDA KIGAAIQEEL KIPCQTGGAV AEILRGIRLH FHSLVKGLTA QSASKAQLGL
GHSYSRAKVK FNVNRVDNMI IQSISLLDQL DKDINTFSMR VREWYGYHFP ELIKIVSDNY
TYCRMAKYIG NRKELSEEKL EEMEEILMDS AKAQAVLDAS RSSMGMDISP IDLINIESFS
SRVISLSEYR KELQEYLRSK MSQVAPSLSA LIGEVVGARL ISHAGSLTNL AKYPASTVQI
LGAEKALFRA LKTRGNTPKY GLIFHSTFIG RAAAKNKGRI SRYLANKCTI ASRIDCFSEI
PTSVFGDKLR EQVEERLAFY ETGEAPRKNL DVMKEAQQEA TEVVTEIKRK LDKKEKKRKK
REKRQLEALA AAQEAEEEEE PTQKKSRENG EEEEEPKKKK KKRHAEPEVS ENGMEEETPS
KKKKQKAAAE EAPQKPKKKK KSKEENES
//
