ID F7EPZ1_MACMU Unreviewed; 519 AA.
AC F7EPZ1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Coiled-coil domain containing 149 {ECO:0000313|Ensembl:ENSMMUP00000035375.3};
GN Name=CCDC149 {ECO:0000313|Ensembl:ENSMMUP00000035375.3,
GN ECO:0000313|VGNC:VGNC:70859};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000035375.3, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000035375.3}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000035375.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CCDC149 family.
CC {ECO:0000256|ARBA:ARBA00005872}.
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DR AlphaFoldDB; F7EPZ1; -.
DR SMR; F7EPZ1; -.
DR Ensembl; ENSMMUT00000042374.3; ENSMMUP00000035375.3; ENSMMUG00000004785.4.
DR VEuPathDB; HostDB:ENSMMUG00000004785; -.
DR VGNC; VGNC:70859; CCDC149.
DR GeneTree; ENSGT00390000015958; -.
DR Proteomes; UP000006718; Chromosome 5.
DR Bgee; ENSMMUG00000004785; Expressed in primary visual cortex and 23 other cell types or tissues.
DR ExpressionAtlas; F7EPZ1; baseline.
DR Gene3D; 1.10.287.1490; -; 1.
DR InterPro; IPR019179; Coiled-coil_dom-contain_pr_149.
DR PANTHER; PTHR21682:SF2; COILED-COIL DOMAIN-CONTAINING PROTEIN 149; 1.
DR PANTHER; PTHR21682; UNCHARACTERIZED; 1.
DR Pfam; PF09789; CC149; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT REGION 343..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 29..254
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 347..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 519 AA; 58202 MW; 84C81574FAB58D11 CRC64;
MEEETMNGDR TESDWQGLVS EYLVCKRKLE SKKEALLILS KELDTCQQER DQYKLMANQL
RERHQSLKKK YREMIDGDPS LPPEKRKQAN LAQLLRDSQD RNKHLGEEIK ELQQRLGEVQ
GDNKLLRMTI AKQRLGDEEI GVRHFAAHER EDLVQQLERA KEQIESLEHD LQASVDELQD
VKEERSSYQD KVERLNQELN HILSGHENRI IDVDALCMEN RYLQERLKQL HEEVNLLKSN
IAKYKNALER RKNSKGQGKS SSSALTGVLS AKQVQDLLSE DHGCSLPATP QSISDLKSLA
TALLETIHEK NMVIQHQRQT NNPEPVKCTS IFPFSATGGK DTILFSDPTL PSGQRSRSPL
LKFVEQPTEN KADPKDGEAQ KQEGDESCAA AEALTAPEDA GRPAVNSPAN QSHGNQCKLF
HPSLPQLPSE EEVNSLGREI IKLTKEQAAA ELEEVRRESP MEGQRSETGP APPDLAIQGE
LPRSHLDSIE ASQPAAEAST PEDGKGIPEG RGTRSTVKT
//
