ID F7F3Y0_MACMU Unreviewed; 694 AA.
AC F7F3Y0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=FAST kinase domains 2 {ECO:0000313|Ensembl:ENSMMUP00000023333.4};
GN Name=FASTKD2 {ECO:0000313|Ensembl:ENSMMUP00000023333.4,
GN ECO:0000313|VGNC:VGNC:72594};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000023333.4, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000023333.4}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000023333.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7F3Y0; -.
DR SMR; F7F3Y0; -.
DR STRING; 9544.ENSMMUP00000023333; -.
DR PaxDb; 9544-ENSMMUP00000023333; -.
DR Ensembl; ENSMMUT00000024934.4; ENSMMUP00000023333.4; ENSMMUG00000017735.4.
DR VEuPathDB; HostDB:ENSMMUG00000017735; -.
DR VGNC; VGNC:72594; FASTKD2.
DR eggNOG; ENOG502QVSD; Eukaryota.
DR GeneTree; ENSGT01030000234607; -.
DR HOGENOM; CLU_025270_0_0_1; -.
DR InParanoid; F7F3Y0; -.
DR OMA; FEIRMDS; -.
DR OrthoDB; 5257459at2759; -.
DR TreeFam; TF352875; -.
DR Proteomes; UP000006718; Chromosome 12.
DR Bgee; ENSMMUG00000017735; Expressed in hindlimb stylopod muscle and 23 other cell types or tissues.
DR GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR GO; GO:0042645; C:mitochondrial nucleoid; IEA:Ensembl.
DR GO; GO:0035770; C:ribonucleoprotein granule; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:Ensembl.
DR GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR GO; GO:1902775; P:mitochondrial large ribosomal subunit assembly; IEA:Ensembl.
DR GO; GO:0000963; P:mitochondrial RNA processing; IBA:GO_Central.
DR GO; GO:0032543; P:mitochondrial translation; IEA:Ensembl.
DR GO; GO:0070131; P:positive regulation of mitochondrial translation; IEA:Ensembl.
DR GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IBA:GO_Central.
DR InterPro; IPR013579; FAST_2.
DR InterPro; IPR010622; FAST_Leu-rich.
DR InterPro; IPR013584; RAP.
DR PANTHER; PTHR21228:SF1; FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR21228; FAST LEU-RICH DOMAIN-CONTAINING; 1.
DR Pfam; PF06743; FAST_1; 1.
DR Pfam; PF08368; FAST_2; 1.
DR Pfam; PF08373; RAP; 1.
DR SMART; SM00952; RAP; 1.
DR PROSITE; PS51286; RAP; 1.
PE 4: Predicted;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 619..676
FT /note="RAP"
FT /evidence="ECO:0000259|PROSITE:PS51286"
SQ SEQUENCE 694 AA; 79697 MW; AFED854CEC655212 CRC64;
MNNKAGSFLW NLRQFSTLVP TSRTRRLYPL GLCKTKIVHS NWNLLNNFHN RMRSTDIFRY
LFQDAFILKS DVGFQTRGIS TVTALRIDRL LYAKRLFFDS KHSLVSVDKF NGELKKVNLH
HEVSSEGVLT KETKPNRISS RKLSEECNSL SDVLDAFTKA PTFPSSNYFT AMWTIAKRLT
DDQKRFEKRL MFSHPAFNQL CEHMMREAKI IQYKCLLFSL YSIVKLGIPQ NTLLVQTLLR
VTQERINEYD EICLSVLSSV LEVMEPCKNV HVLQMGFRIL VDQQVWKIED VFTLQVVMKC
IGKDAPIALK RKLEMKALRE LDRFSLLNSQ RMFEVLAAMN HRSLILLNEC SKVVLDNIHG
CPSKIIINIL QSCKDLQYYN LDLFNGLADY VAATFDVWKL KKVLFILILF ENLGFRHVGL
MDLFMKRIVE DPESLNMKNI LSILHTYSSL NHVYKCQNKE QFLEVMASAL TGYLHSVSSE
NLLDAVYSFC LMNYFPLASF NQLLQKDVIS ELLTSDDMKK NVHKLHILDT CLKLDDTVCL
KDIALSLPQL PRELPPSHPN AKVAEVLSSL LGSEGYFSKD VHLPHSYHID FEIRMDTNRN
QVLPFSDVDT ASATAIQRVA VLCVSRSAYC LGSSHPRGFL AMKMRHLNAM GFHVILVNNW
EMDKLEMEDA ITFLKTKIYS VEALPVAAVN LQST
//
