ID F7F5H1_MACMU Unreviewed; 644 AA.
AC F7F5H1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Lamin tail domain containing 2 {ECO:0000313|Ensembl:ENSMMUP00000028528.4};
GN Name=LMNTD2 {ECO:0000313|Ensembl:ENSMMUP00000028528.4,
GN ECO:0000313|VGNC:VGNC:74380};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000028528.4, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000028528.4}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000028528.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014968708.1; XM_015113222.1.
DR AlphaFoldDB; F7F5H1; -.
DR SMR; F7F5H1; -.
DR STRING; 9544.ENSMMUP00000028528; -.
DR Ensembl; ENSMMUT00000030486.4; ENSMMUP00000028528.4; ENSMMUG00000021664.4.
DR GeneID; 720799; -.
DR CTD; 256329; -.
DR VEuPathDB; HostDB:ENSMMUG00000021664; -.
DR VGNC; VGNC:74380; LMNTD2.
DR eggNOG; KOG0977; Eukaryota.
DR GeneTree; ENSGT00390000012150; -.
DR HOGENOM; CLU_432519_0_0_1; -.
DR InParanoid; F7F5H1; -.
DR OMA; HLTVWGE; -.
DR OrthoDB; 4604818at2759; -.
DR TreeFam; TF337768; -.
DR Proteomes; UP000006718; Chromosome 14.
DR Bgee; ENSMMUG00000021664; Expressed in spermatid and 16 other cell types or tissues.
DR GO; GO:0005638; C:lamin filament; IBA:GO_Central.
DR GO; GO:0030527; F:structural constituent of chromatin; IBA:GO_Central.
DR Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR PANTHER; PTHR19956; LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR19956:SF5; LAMIN TAIL DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00932; LTD; 1.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR PROSITE; PS51841; LTD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 360..478
FT /note="LTD"
FT /evidence="ECO:0000259|PROSITE:PS51841"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..566
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 120..179
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 241..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 71205 MW; 9912886BAF2116F6 CRC64;
MAPKSGQGVE EAEEEALLSP TERESVSGHL GPPAGAPAAP ETPTCLPDTT PHPTRAACSA
DLQLALESLD PRTLRLLWKQ RELEIQALRW AVQNGKDTRL CHILEEVAGI SPKRSSHSQE
KFLQNQVQKL TLELKEQKER AQWEKEHLEE RLLQTTRTLQ EVEAELQNLQ KSCLLQLARS
SWVGRMLRSQ TGSVEVVTAE TLMDPSDLSE NIQAPTGEGF RLEDVDWNSI AHRYPNLFIS
LEPNSKQKQP RPWPQLDTGS SESSGKHSER HHKTVEWGCL PCLNTSSSGG VDSDSSSCRP
GLPSLVQVVG HPPRDHRASS KQALVQARSS SRDLEDLQKI HSPRHGGPLL APQPCTDPDH
WSPEHLQSPT GLKIVAVSCR EKFVRIFNPS QESTADLSGM VLKQVVRGLP ERLYRFPPGT
LLAPRHHITV WGEGTRSAKK PPRASSGREP VPLLSSRGCA TLLLSPKGEV LSEHQIPRRE
TPAPRVFDDG TDLSIDRFPL PEVGPGADTC KPQRPPRPLR KGRVREPRVS RRRPRTRGLL
PPMSSGKLFH AREGPTRPEN PEIPVPQHLP TIPGDPTLPS PPAEAGLGLE NCRLRKEHQV
RVCRKSVDRS CPLVALSVQS TAESRFGFRF LSCLPVTADT CRGA
//
