ID F7FKA5_ORNAN Unreviewed; 586 AA.
AC F7FKA5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=SSX family member 2 interacting protein {ECO:0000313|Ensembl:ENSOANP00000005563.2};
GN Name=SSX2IP {ECO:0000313|Ensembl:ENSOANP00000005563.2};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000005563.2, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000005563.2, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000005563.2,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000005563.2}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000005563.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC {ECO:0000256|ARBA:ARBA00004536}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the ADIP family.
CC {ECO:0000256|ARBA:ARBA00009291}.
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DR AlphaFoldDB; F7FKA5; -.
DR STRING; 9258.ENSOANP00000005563; -.
DR Ensembl; ENSOANT00000005564.3; ENSOANP00000005563.2; ENSOANG00000003514.3.
DR eggNOG; ENOG502QQJF; Eukaryota.
DR GeneTree; ENSGT00390000007688; -.
DR OMA; QHCKEMI; -.
DR TreeFam; TF332889; -.
DR Proteomes; UP000002279; Chromosome 4.
DR Bgee; ENSOANG00000003514; Expressed in testis and 8 other cell types or tissues.
DR GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR GO; GO:0034451; C:centriolar satellite; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR InterPro; IPR021622; Afadin/alpha-actinin-bd.
DR PANTHER; PTHR46507; AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN; 1.
DR PANTHER; PTHR46507:SF1; AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN; 1.
DR Pfam; PF11559; ADIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT REGION 505..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 134..221
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 263..290
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 380..407
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 586 AA; 68309 MW; 4206902F7028AA49 CRC64;
MGDWKTITVP VLQSSVSDSK SISQYTSETK MSPSSSYTQR VLCSSVPLTK SVHNFFSAFC
TEENVEQSIS YLNQELTTLG FPSLYEESKG KETKRELSII AVLNCINELL LLQHKNLRTQ
EDVETQNLKL GSDMDHLQSC YSKLKEQLET SRREMVGLQE RDRQLQCKNR NLHQLLKNEK
DEVQKLQNII ASRATQYNHD MKRKEREYNK LKERLHQLVM NKKDKKTAMD VLNYVGRADG
KRGAWRTDKT EARNEDEMYK VLLSDYEQRQ KQILLENAEL KKVLQQMKKE MISILTPQKQ
KPKGKVEESC GAVLSDMEED AGDLSKDSNM WELSCETARE QLTNSIRKQW RILKSHVEKL
DNQVSQVHFG AFNDEDVISR QDHEQETEKL ELEIQQCKEM IKNQQQLLQQ QLTVDDDTSS
LFQDCYLLEE KERLQEEWML FKEQKKNFER ERRNFTEAAI QLGVEKYWCL NISQVWNSRF
LVNFRVKVAH IRKSWLSNSF VASVPPGSRG RGLKGSSAQK KPENHRRPHC FPVSSFEAAR
TVWDDQASDF KDRLRCPLTL GTSEFQQGRD RPEPTISASW CPSPRA
//
