ID F7H6G2_CALJA Unreviewed; 218 AA.
AC F7H6G2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 14 {ECO:0000256|RuleBase:RU369059};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000006418.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000006418.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000006418.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Inhibitor of PPP1CA. {ECO:0000256|RuleBase:RU369059}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU369059};
CC Peripheral membrane protein {ECO:0000256|RuleBase:RU369059}.
CC -!- SIMILARITY: Belongs to the PP1 inhibitor family.
CC {ECO:0000256|ARBA:ARBA00005483, ECO:0000256|RuleBase:RU369059}.
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DR AlphaFoldDB; F7H6G2; -.
DR STRING; 9483.ENSCJAP00000006418; -.
DR Ensembl; ENSCJAT00000006778.3; ENSCJAP00000006418.3; ENSCJAG00000069566.2.
DR eggNOG; ENOG502RYQF; Eukaryota.
DR GeneTree; ENSGT00950000182985; -.
DR InParanoid; F7H6G2; -.
DR OrthoDB; 5321897at2759; -.
DR TreeFam; TF105546; -.
DR Proteomes; UP000008225; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0042325; P:regulation of phosphorylation; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.150.220; CPI-17; 1.
DR InterPro; IPR008025; CPI-17.
DR InterPro; IPR036658; CPI-17_sf.
DR PANTHER; PTHR16188; PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C; 1.
DR PANTHER; PTHR16188:SF6; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14C; 1.
DR Pfam; PF05361; PP1_inhibitor; 1.
DR SUPFAM; SSF81790; Myosin phosphatase inhibitor 17kDa protein, CPI-17; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU369059};
KW Phosphoprotein {ECO:0000256|RuleBase:RU369059};
KW Protein phosphatase inhibitor {ECO:0000256|ARBA:ARBA00023272,
KW ECO:0000256|RuleBase:RU369059};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT REGION 30..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 23207 MW; F239F7DE7C962A12 CRC64;
MKFLCQTVYI SEIYGGAGAG ELFARGCGAG GDSGAGRAPP APPPGHSRVR AHGDLSVVTG
SREAAGGAGG GARVFFQSPR GCAEGSTGSS SGSGSSWEDS APVATTAAAG QVQQQQRRRH
QQGKVTVKYD RKELRKQLVL EEWILEQLGQ LYGCEEEEVP EVETDIDDLL DADSDEERAS
KLQEALVDCS KPTEEFIKEL LSRIRGMRKL SPPQKKSA
//
