ID F7J6K1_9GAST Unreviewed; 152 AA.
AC F7J6K1;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Engrailed {ECO:0000313|EMBL:BAK40159.1};
DE Flags: Fragment;
OS Nipponacmea fuscoviridis.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Nipponacmea.
OX NCBI_TaxID=225302 {ECO:0000313|EMBL:BAK40159.1};
RN [1] {ECO:0000313|EMBL:BAK40159.1}
RP NUCLEOTIDE SEQUENCE.
RA Hashimoto N., Kurita Y., Wada H.;
RT "Co-option of the dpp signaling pathway and evolution of the gastropod
RT operculum.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the engrailed homeobox family.
CC {ECO:0000256|ARBA:ARBA00010896}.
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DR EMBL; AB639757; BAK40159.1; -; mRNA.
DR AlphaFoldDB; F7J6K1; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000747; Homeobox_engrailed.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR000047; HTH_motif.
DR PANTHER; PTHR24341; HOMEOBOX PROTEIN ENGRAILED; 1.
DR PANTHER; PTHR24341:SF6; HOMEOBOX PROTEIN INVECTED-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00026; ENGRAILED.
DR PRINTS; PR00024; HOMEOBOX.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 81..141
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 83..142
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 19..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..90
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAK40159.1"
FT NON_TER 152
FT /evidence="ECO:0000313|EMBL:BAK40159.1"
SQ SEQUENCE 152 AA; 17976 MW; 3692A71E0D4B0731 CRC64;
NQILDDERRI TAPFLAHRIS MKLPTSPPFR ERKEIPTPKS PEPESQKKST ELWPAWVFCT
RYSDRPSSGP RCRKPKKKQT EMDKRPRTAF TNDQLQRLKR EFDENRYLTE TRRQNLATEL
GLHESQVKIW FQNKRAKLKK STGTTNPLAL KL
//
