ID F7JIK2_9FIRM Unreviewed; 700 AA.
AC F7JIK2;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=HMPREF0988_00156 {ECO:0000313|EMBL:EGN33644.1};
OS Lachnospiraceae bacterium 1_4_56FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658655 {ECO:0000313|EMBL:EGN33644.1, ECO:0000313|Proteomes:UP000004289};
RN [1] {ECO:0000313|EMBL:EGN33644.1, ECO:0000313|Proteomes:UP000004289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1_4_56FAA {ECO:0000313|EMBL:EGN33644.1,
RC ECO:0000313|Proteomes:UP000004289};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 1_4_56FAA.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGN33644.1}.
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DR EMBL; ACTN01000003; EGN33644.1; -; Genomic_DNA.
DR AlphaFoldDB; F7JIK2; -.
DR STRING; 658655.HMPREF0988_00156; -.
DR PATRIC; fig|658655.3.peg.152; -.
DR eggNOG; COG1033; Bacteria.
DR HOGENOM; CLU_007352_0_0_9; -.
DR OrthoDB; 9782006at2; -.
DR Proteomes; UP000004289; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 174..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..592
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..675
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 80..327
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 393..675
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 700 AA; 77426 MW; 9FB2575D393FA87B CRC64;
MVKVGKGIAR HRVLILILSI LLLIPSMIGM ARTKINYDLL SYLPGNLETV KGQDILVDEY
GMGAFSMVVV ENMELKDVQK LEEEFSEVEH VKDVLWYDDA ADISLPVEMI PKDLRETFFR
GDATMMLVLF DNTTSSDEAM GAVSELRRIA DERCFIGGMT GVVTDIKNLC DEELPIYVVI
AVLLSLLVLE LTSTSYLTPL LFLFSIGAAI LYNLGSNVFL GETSYITKAL TAILQLGVTM
DYSIFLLNSY EENKRRFPGE KERAMGHAIA NTFKSVVGSS VTTIAGFAAL CFMTFALGRD
LGIVMAKGVV IGVLCCVTLL PSLVLIFDKL IEKTKHKPLI KSMDRPSAFI TKHYKVWIVI
FLIMLFPAIY GNNHTQIYYD IAKSLPDTLA SNVANEKLKE DFEMSNMHMI LMDKDMDQKA
KADMLEEVDK IDGVKWSLGL DSLIGPMVPD SMIPEDVKEM LQSDNYELAF ICSEYESATD
QVNDQIAAID KIVKSYDDTA MVIGEAPLMK DLQDVTDVDL INVNAVSMIA IFLIIMIVFK
SISLPVILVA VIEFAIAVNM AVPYYSGISL PFVASIVIGT IQLGATVDYA ILMTSRYQKE
RMLRGQTKKD AIAIAHKTSM PSIISSGLSF FAATFGVACY SKVDMIGSIC TLLARGALIS
MCVVILVLPA MLMIFDKVIL KTTFGFGKQK QENQIQQTQN
//
