ID   F7K112_9FIRM            Unreviewed;       245 AA.
AC   F7K112;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|ARBA:ARBA00018893};
GN   ORFNames=HMPREF0991_03077 {ECO:0000313|EMBL:EGN44381.1};
OS   Lachnospiraceae bacterium 2_1_58FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658082 {ECO:0000313|EMBL:EGN44381.1, ECO:0000313|Proteomes:UP000004820};
RN   [1] {ECO:0000313|EMBL:EGN44381.1, ECO:0000313|Proteomes:UP000004820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2_1_58FAA {ECO:0000313|EMBL:EGN44381.1,
RC   ECO:0000313|Proteomes:UP000004820};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA   Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA   MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA   Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 2_1_58FAA.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGN44381.1}.
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DR   EMBL; ACTO01000052; EGN44381.1; -; Genomic_DNA.
DR   AlphaFoldDB; F7K112; -.
DR   PATRIC; fig|658082.3.peg.3094; -.
DR   HOGENOM; CLU_026910_4_0_9; -.
DR   Proteomes; UP000004820; Unassembled WGS sequence.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00009; AAA; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050; CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA; 1.
DR   PANTHER; PTHR30050:SF2; CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   PRINTS; PR00051; DNAA.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48295; TrpR-like; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|RuleBase:RU004227}.
FT   DOMAIN          1..176
FT                   /note="Chromosomal replication initiator protein DnaA"
FT                   /evidence="ECO:0000259|Pfam:PF00308"
SQ   SEQUENCE   245 AA;  28030 MW;  16F60781FEE5855B CRC64;
     MHSIAHFILE KDPTKKVLYV TSETFTNELI DALKIGKNGN ELAMTTFREK YRNNDVLLID
     DIQFIIGKES TQEEFFHTFN HLHVSGKQII ISSDKPPKDI ETLEARLRTR FEWGLIADIS
     SPDYETRMAI LRKKEELDGL ERYHIPDEVM QYIANNITSN IRELEGSLNK LIALANLENK
     PIDIPLAAEA LKDMISPNNT REITPELIIE VVSDHFNVPA AELKGKNETL RLFCLVRLLC
     ISAVK
//