ID F7MAN7_9BACE Unreviewed; 891 AA.
AC F7MAN7;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Beta-galactosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF0127_04521 {ECO:0000313|EMBL:EGM96455.1};
OS Bacteroides sp. 1_1_30.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=457387 {ECO:0000313|EMBL:EGM96455.1, ECO:0000313|Proteomes:UP000004085};
RN [1] {ECO:0000313|EMBL:EGM96455.1, ECO:0000313|Proteomes:UP000004085}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1_1_30 {ECO:0000313|EMBL:EGM96455.1,
RC ECO:0000313|Proteomes:UP000004085};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Yandava C., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Bacteroides sp. 1_1_30.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGM96455.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADCL01000095; EGM96455.1; -; Genomic_DNA.
DR RefSeq; WP_004299901.1; NZ_GL945104.1.
DR AlphaFoldDB; F7MAN7; -.
DR GeneID; 29456224; -.
DR PATRIC; fig|457387.3.peg.4598; -.
DR HOGENOM; CLU_006501_5_0_10; -.
DR Proteomes; UP000004085; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR032311; DUF4982.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR021720; Malectin_dom.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF16355; DUF4982; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF11721; Malectin; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..891
FT /note="Beta-galactosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003359911"
FT DOMAIN 46..172
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 193..296
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 304..594
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 634..682
FT /note="DUF4982"
FT /evidence="ECO:0000259|Pfam:PF16355"
FT DOMAIN 761..873
FT /note="Malectin"
FT /evidence="ECO:0000259|Pfam:PF11721"
SQ SEQUENCE 891 AA; 102577 MW; 1B7BF23A6C398551 CRC64;
MKKFLYIFIL LFIVGWAQAQ QRVVYTINDG WKFTKGSPFE AQLAGCDDSS WETVNIPHTW
NNKDADDETP GFYRGPAWYR KQLFVDKSQE GRQAVIYFEG ANQEVRFYLN GQFVGEHKGG
YTRFCFDITS HLRYGQENLF TIYVNNVYNP NIPPLSADFT FFGGIYRDVY LQFMNPVHIA
TNDYASSGVY IRTPEVNNSA ASVEITTLLT NNTLQPAEIR VENVICDADG KEVKKTHAEI
KLASGETKTD ISKKIKIDSP RLWDIDDPYR YMVYTRILDK KKGTLLDEVV NPLGLRWFKF
DSEKGFFLNG KGRKLIGTAR HQDYFQKGNA LRDELHVQDV LLLKEMGGNF LRVSHYPQDP
VIMEMCDKLG IVTSVEIPVV NAVTETEEFL QNSVEMAKEM VRQDFNRPSV MIWGYMNEIF
LRRPYTEGKQ LEDYYRFTEK VARALEATIR EEDPSRYTMM AYHNMPQYYE DAHLTEIPMI
QGWNLYQGWY EPDINEFQRL LDRAHKVYKG KVLMVTEYGP GVDPGLHSYQ PERFDFSQEY
GLVYHKHYLR EMMKRPFIAG SSLWNLNDFY SESRVDAVPH VNNKGVVGLN REKKDVYWFY
KTALSRRPIL VIGNREWKSR GGVVNTAQKE CIQSVPVFSN AEEVELFVNN KSLGKKKVED
NYALFDVPFV GGENLLEAVA VAGDSKLRDM LRIQFQLVGS QLKDEAIPFT EINVMLGSPR
YFEDRTANVA WIPEQEYKPG SWGFVGGTSY RRKTGFGSML GSDIDILGTD MNPIFQTQRV
GIKSFKADVP NGEYSVYLYW AELESDKERE ALVYNLGADS EQTFAGNRSF GISMNGTTVL
DDFNIARDYG YARAVIKKFV VTVKDGKGLS VDFHKKEGEP ILNAIRIYRN Y
//
