ID F7QSE9_9LACO Unreviewed; 469 AA.
AC F7QSE9;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=LSGJ_00828 {ECO:0000313|EMBL:EGM52406.1};
OS Ligilactobacillus salivarius GJ-24.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1041521 {ECO:0000313|EMBL:EGM52406.1, ECO:0000313|Proteomes:UP000003074};
RN [1] {ECO:0000313|EMBL:EGM52406.1, ECO:0000313|Proteomes:UP000003074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GJ-24 {ECO:0000313|EMBL:EGM52406.1,
RC ECO:0000313|Proteomes:UP000003074};
RX PubMed=21742893; DOI=10.1128/JB.05616-11;
RA Cho Y.J., Choi J.K., Kim J.H., Lim Y.S., Ham J.S., Kang D.K., Chun J.,
RA Paik H.D., Kim G.B.;
RT "Genome Sequence of Lactobacillus salivarius GJ-24, a Probiotic Strain
RT Isolated from Healthy Adult Intestine.";
RL J. Bacteriol. 193:5021-5022(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGM52406.1}.
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DR EMBL; AFOI01000002; EGM52406.1; -; Genomic_DNA.
DR AlphaFoldDB; F7QSE9; -.
DR PATRIC; fig|1041521.3.peg.829; -.
DR Proteomes; UP000003074; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EGM52406.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 161..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 181..233
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 248..464
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 221..248
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 469 AA; 53600 MW; 2B0BA6B957592650 CRC64;
MVFFHLTKEM TYENAWQQMQ GYAYTLRKEA LKLTTDKAGK TIIVLNVSQL KATEKLLSAQ
NTHFTIYTSR TDVLYPDNSV IRENRSISKA DWKKLTAGNV VKRKQDFRPR KSKSEVDGSD
VKITDIYAPC FDYQGNLVAV IKVGEDLSNI TQNLQIIRRN VVLTVAFAIL VGVILSIIIA
HFLTKKIARL RNATDLVAAG NFDVHLDTNG DSELDKLTLD FNSMVQSLRE SNEEIKRQEE
RRRQFFADAA HEMRTPLTTI NGLLEGLAYD AIPEESKEKS IELMRNETKR LIRLVNENLD
YEKIRSGQIE LSKTEFDVVQ VLNNIIKQLR NKAEQVGDKF EVYTPDKLMV YADYDRLVQI
IFNITQNAIQ FTENGVISIS AEKGNEETII RISDNGIGMN EEQLRNIWER YYKADPSRKN
TKYGESGLGL SIVHQLMQLH QGSVTVESKE GKGTTFTLRF PNKNKLSKI
//
