ID F7S4F1_9PROT Unreviewed; 660 AA.
AC F7S4F1;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:EGO95964.1};
GN ORFNames=APM_1202 {ECO:0000313|EMBL:EGO95964.1};
OS Acidiphilium sp. PM.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acidiphilium.
OX NCBI_TaxID=1043206 {ECO:0000313|EMBL:EGO95964.1, ECO:0000313|Proteomes:UP000004823};
RN [1] {ECO:0000313|EMBL:EGO95964.1, ECO:0000313|Proteomes:UP000004823}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PM {ECO:0000313|EMBL:EGO95964.1,
RC ECO:0000313|Proteomes:UP000004823};
RX PubMed=21914891; DOI=10.1128/JB.05386-11;
RA San Martin-Uriz P., Gomez M.J., Arcas A., Bargiela R., Amils R.;
RT "Draft Genome Sequence of the Electricigen Acidiphilium sp. Strain PM (DSM
RT 24941).";
RL J. Bacteriol. 193:5585-5586(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGO95964.1}.
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DR EMBL; AFPR01000107; EGO95964.1; -; Genomic_DNA.
DR AlphaFoldDB; F7S4F1; -.
DR HOGENOM; CLU_009289_6_2_5; -.
DR Proteomes; UP000004823; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:EGO95964.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..183
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 235..526
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 660 AA; 70560 MW; 664ABFFC153D12F6 CRC64;
MEHVRVTSPD LARRAAIGVL HSRLAAGFAG FVLIYLLLAA RVVYVTVVHP VPPDKAAIAA
QTPSTTVVLP PPARAEITDR NGEILAVSLP AAALYANPKQ VEDPGVAARE IAAVIPGLDP
GFLEARLADR SRDFVYLDRK LTASQELAVN RLGIPGVYFE NTERRHYPEG NLAAHILGGV
TPDQRGIAGV EDWFNKRLTS APGKPLRLSI DIGAEGIVRQ AIWQAMSDYD AKGACGIVIS
ARTGRVLAMA SVPDYNADDL GSAPADARFN RCVSGDYEPG SVFKLQTLSM AINSGMIQPW
DRFNTTHPLH VGRFTVTDFE PAHIWMAVPH ILAVSSNIGA SRIATILGPQ IQRAWLRKLG
FFRRPPIQLP EATPPMYHPK SSWKLLTTMT VSFGNGIAMS PLQLISAVVP VVNGGIWYPP
TLLDHGKRSA GVRVMSERTS LIMRKMMRNV VTAPDGTGVY ARVPGYLVGG KTGTAQVVGP
NGRYLQHLNN ASFMAAFPMN DPRYVVYVVV LQPHATKQML PFCHGFTTGG YVAAPAVAQI
ISRIGPMLGI MPLSGQTLAE AQAALSIPLD PPAPPGRLAL GPGHLFPPGA SKYAYILAHQ
TPPANMDVAA HDQALARTEM WQPLAPAAQT VSLPAAPASS AHTLGHRIMN IALPVTHAGG
//
