ID F7V790_CLOSS Unreviewed; 652 AA.
AC F7V790;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Predicted nucleoside-diphosphate sugar epimerase {ECO:0000313|EMBL:BAK48518.1};
GN OrderedLocusNames=CXIVA_25490 {ECO:0000313|EMBL:BAK48518.1};
OS Clostridium sp. (strain SY8519).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1042156 {ECO:0000313|EMBL:BAK48518.1, ECO:0000313|Proteomes:UP000008937};
RN [1] {ECO:0000313|Proteomes:UP000008937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY8519 {ECO:0000313|Proteomes:UP000008937};
RX PubMed=21914882; DOI=10.1128/JB.05637-11;
RA Yokoyama S., Oshima K., Nomura I., Hattori M., Suzuki T.;
RT "Complete genomic sequence of the O-desmethylangolensin-producing bacterium
RT Clostridium rRNA cluster XIVa strain SY8519, isolated from adult human
RT intestine.";
RL J. Bacteriol. 193:5568-5569(2011).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; AP012212; BAK48518.1; -; Genomic_DNA.
DR RefSeq; WP_013978471.1; NC_015737.1.
DR AlphaFoldDB; F7V790; -.
DR STRING; 1042156.CXIVA_25490; -.
DR KEGG; cls:CXIVA_25490; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_5_2_9; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000008937; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008937};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 297..608
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 652 AA; 73872 MW; BF2C51FA4763CA16 CRC64;
MSENAKKIKK RLEHWEVVSL LLAVYDFLAV TVSYFAALWI RFDCSFNLIE HDYLHAYYRT
ILIYAGCCII VFWLTRLYKS IWRFASYSEL MRMILATVIT GASYAACMSG FVRRMPVSYF
VFGIIIQFVL TLGIRFSYRF ILLLRARRNE DEAGKNVMLI GAGAAGQMIF RDIRRSRETS
ETVCCFIDDN PNKWGRYIDN VPVFGGRESI LEAVRKFEIE KIYVAIPSAA PKDKREILRI
CNETSCELMN LPGMYQIYTG QVSISKMKPV QIEDLLGRDP IRPDMKEVFK YITGKVVLIT
GVGSIGSELA RQIASHHPKH LILFDVYENN AYEVQQELKK KYPDLELDTI IGSVRDSRKV
FQLFEKFRPE IVYHAAAHKH VPLMEDSPCE AIKNNAIGTY KTAYAAMAHG CKRFVLISTD
KAVNPTNIMG ASKRLCEMII QAFDAKIKEG KAYEIPQLFT HGVKDAMTAP EVIEALKKTS
TEFVAVRFGN VLGSNGSVIP LFKKQIAAGG PVTVTHPDII RYFMTIPEAV SLVLLAGTYA
KGGEIFVLDM GEPVKIDTLA RNLIRLSGYT PDVDIKIEFT GLRKGEKLFE EKLMAEEGLR
KTKNELIHIG CPIPFDINEF LGQLEGLLNA AYKNKDDMRE RVQKVVVTYH PA
//
