ID F7VIM2_9PROT Unreviewed; 502 AA.
AC F7VIM2;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=DNA gyrase modulator TldD {ECO:0000313|EMBL:GAA10217.1};
GN ORFNames=ATPR_3221 {ECO:0000313|EMBL:GAA10217.1};
OS Acetobacter tropicalis NBRC 101654.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acetobacter.
OX NCBI_TaxID=749388 {ECO:0000313|EMBL:GAA10217.1, ECO:0000313|Proteomes:UP000004319};
RN [1] {ECO:0000313|EMBL:GAA10217.1, ECO:0000313|Proteomes:UP000004319}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 101654 {ECO:0000313|EMBL:GAA10217.1,
RC ECO:0000313|Proteomes:UP000004319};
RX PubMed=21554859; DOI=10.1016/j.bbrc.2011.04.126;
RA Matsutani M., Hirakawa H., Nishikura M., Soemphol W., Ali I.A.I.,
RA Yakushi T., Matsushita K.;
RT "Increased number of Arginine-based salt bridges contributes to the
RT thermotolerance of thermotolerant acetic acid bacteria, Acetobacter
RT tropicalis SKU1100.";
RL Biochem. Biophys. Res. Commun. 409:120-124(2011).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA10217.1}.
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DR EMBL; BABS01000190; GAA10217.1; -; Genomic_DNA.
DR AlphaFoldDB; F7VIM2; -.
DR Proteomes; UP000004319; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR025502; TldD.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR PIRSF; PIRSF004919; TldD; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670}.
FT DOMAIN 63..123
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 150..259
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 267..500
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 502 AA; 52816 MW; 197559ACF5E167C7 CRC64;
MLGDCGPRTL VLSGVLFMSS PLSSPGALAV TDDLFFKRPN ALLQRDEAEG LTRDALTGMD
DGELFLEYRE SESIALDDGV IRSASFDTSC GFGLRSVLGE ETGFAHSDDL SRSALKRAAD
AVSAVRNGRS GTMADAPRST NTRLYTDANP LGDTDFAARS GLLSRIDAYA RGKDSRVVQV
MASLSGEWQA VQIIRADGVR VADLRPLVRL NVSVVVEQGG KRESGSHGLG GRYEINRLLE
EPTWQGAVDE ALRQALVALE ARPAPAGEME VVLGAGWPGI LLHEAVGHGL EGDFNRKGTS
AFAGLMGKRV AAPGVTVIDD GSLPDRRGSL TVDDEGTPTG RTVLIEDGIL TGYLQDRLNA
RLMHMAPTGN GRRQSYAHVP LPRMTNTLML PGQASTEDMI RSMKRGLYAV HFGGGQVDIT
SGKFVFSASE AYLVEDGKIT APVKGATLIG SGAEAMTQVS MIGKDMELDP GIGTCGKAGQ
GVPVGVGQPT LKMAGLTVGG TA
//
