ID F7XP10_METZD Unreviewed; 293 AA.
AC F7XP10;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=CoB/CoM heterodisulfide reductase, subunit B {ECO:0000313|EMBL:AEH60204.1};
DE EC=1.8.98.1 {ECO:0000313|EMBL:AEH60204.1};
GN OrderedLocusNames=Mzhil_0328 {ECO:0000313|EMBL:AEH60204.1};
OS Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5)
OS (Methanohalophilus zhilinae).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosalsum.
OX NCBI_TaxID=679901 {ECO:0000313|EMBL:AEH60204.1, ECO:0000313|Proteomes:UP000006622};
RN [1] {ECO:0000313|Proteomes:UP000006622}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4017 / NBRC 107636 / OCM 62 / WeN5
RC {ECO:0000313|Proteomes:UP000006622};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA Ovchinnikova G., Daligault H., Detter J.C., Han C., Tapia R., Larimer F.,
RA Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA Wu D., Spring S., Schueler E., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Methanosalsum zhilinae DSM 4017.";
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Cofactor metabolism; coenzyme M-coenzyme B heterodisulfide
CC reduction; coenzyme B and coenzyme M from coenzyme M-coenzyme B
CC heterodisulfide: step 1/1. {ECO:0000256|ARBA:ARBA00004808}.
CC -!- SIMILARITY: Belongs to the HdrB family.
CC {ECO:0000256|ARBA:ARBA00010431}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002101; AEH60204.1; -; Genomic_DNA.
DR RefSeq; WP_013897643.1; NC_015676.1.
DR AlphaFoldDB; F7XP10; -.
DR STRING; 679901.Mzhil_0328; -.
DR GeneID; 10821933; -.
DR KEGG; mzh:Mzhil_0328; -.
DR HOGENOM; CLU_052147_1_0_2; -.
DR OrthoDB; 144689at2157; -.
DR UniPathway; UPA00647; UER00700.
DR Proteomes; UP000006622; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051912; F:CoB--CoM heterodisulfide reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1050.140; -; 1.
DR Gene3D; 3.40.50.11810; -; 1.
DR InterPro; IPR017678; CoB/CoM_hetero-S_Rdtase_bsu.
DR InterPro; IPR004017; Cys_rich_dom.
DR NCBIfam; TIGR03288; CoB_CoM_SS_B; 1.
DR PANTHER; PTHR42947; COB--COM HETERODISULFIDE REDUCTASE SUBUNIT B 1; 1.
DR PANTHER; PTHR42947:SF1; COB--COM HETERODISULFIDE REDUCTASE SUBUNIT B 1; 1.
DR Pfam; PF02754; CCG; 2.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Methanogenesis {ECO:0000256|ARBA:ARBA00022994};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AEH60204.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006622}.
FT DOMAIN 5..86
FT /note="Cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF02754"
FT DOMAIN 148..240
FT /note="Cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF02754"
SQ SEQUENCE 293 AA; 32730 MW; 8897ECDB7A458D11 CRC64;
MTKMALFLGC IVPNRYPGIE KATNLCLERL SIDCIELEDA SCCPAPGVFR SFDKTTWLTI
AARNISLAEK LDRDILTICN GCYGSLNEAN AQLKEQPQLR KMVNEHLEKI GFEFRGQIRV
RHIIEFLSEE LGPEQIREMV THPLNLRVAV HYGCHMIKPS QHRAIDSVER PHFFDELVEA
TGAESVDYTD KSECCGAGGG VRSGLHEKSL EMAGHKLSII DEAGVDCIVD ACPFCHMQFD
SGQAELNDLK GTEYRIPVLH YTQLLGLAFG YTPQDLGIDL NITVDEKFTQ LLS
//
