ID F7Y7V9_MESOW Unreviewed; 997 AA.
AC F7Y7V9;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Sarcosine oxidase, alpha subunit family {ECO:0000313|EMBL:AEH86341.1};
GN OrderedLocusNames=Mesop_1860 {ECO:0000313|EMBL:AEH86341.1};
OS Mesorhizobium opportunistum (strain LMG 24607 / HAMBI 3007 / WSM2075).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=536019 {ECO:0000313|EMBL:AEH86341.1, ECO:0000313|Proteomes:UP000001623};
RN [1] {ECO:0000313|EMBL:AEH86341.1, ECO:0000313|Proteomes:UP000001623}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 24607 / HAMBI 3007 / WSM2075
RC {ECO:0000313|Proteomes:UP000001623};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Chertkov O., Misra M., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ovchinnikova G., Mavrommatis K.M., Tiwari R.P.,
RA Howieson J.G., O'Hara G.W., Nandasena K.G., Woyke T.;
RT "Complete sequence of Mesorhizobium opportunistum WSM2075.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; CP002279; AEH86341.1; -; Genomic_DNA.
DR RefSeq; WP_013893067.1; NC_015675.1.
DR AlphaFoldDB; F7Y7V9; -.
DR STRING; 536019.Mesop_1860; -.
DR KEGG; mop:Mesop_1860; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0446; Bacteria.
DR HOGENOM; CLU_011963_0_0_5; -.
DR Proteomes; UP000001623; Chromosome.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 172..451
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 516..596
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 614..879
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 904..989
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 997 AA; 107141 MW; 227AEECD91D8E34F CRC64;
MSGGFRIPSA GRLSQAKTAR FSFDGQPYTG IEGDTLASAL LANGVHLVGR SFKYHRPRGI
LSAGAEEPNA LVQIVRDDAR KTPNVRATVQ ELYDGLAANS QNRWPSLSFD IGAVNDIASP
MFSAGFYYKT FMWPKAAWKS FYEPKIREAA GLGVSPDKPD PDHYSSRYAH CDVLVLGGGA
AGIAAALAAA ETGVRVILAD EQVEFGGSLR FESGAKIDGQ DGFAWAQAAI ARLSAMDNVR
VLSRTTAFGY YAQNFVGLVE RVSDHLKAPG HDLPRERLWQ VRAKRVVLAS GAIERHMVFA
NNDRPGIMLA GAARTFLNHY GVAVGRNVGV YTANDSAYAA AIDLKKAGVN VAAIVDLRDN
PTGPVIDEAR ALGIEINFGR AVIRAGGKLR VSSMTVQPKN GGGERTIPVD AILMSAGWTP
SVHLFSQSRG KVAFNDETKR FVPGIYAQDC VSVGACNGTD GLSATVDEAY AAGAKAAKDA
GAKTAKGAKP KVDASESWSR GMLGAGPGAG PDTTVKAFVD FQNDVTAKDI RQAVHEGMRS
IEHVKRFTTN GMATDQGKTS NMHGLAIAAE TLGKPIPEVG LTTFRAPYTP VTFGAIVSHA
RGPLFDPTRK TAIHPWAEAQ GAVFEDVGQW KRAWYFPKAG EDMHAAVDRE CVAVRNKAGL
FDASTLGKIE VVGPDAAKFM ELLYTNPWEK LEPGRCRYGI MLREDGFIYD DGVVGRLAPD
RFHVTTTTGG APRVMNHMED YLQTEFPHLN VWLTSITEQW AVIAVQGPKS RDIIAPLVEG
IDMSDEALPH MSVREGKICG VPTRLFRMSF TGERGFEVNV PADYGQAVWE ALWAEGQKHG
AAAYGTEAMH VLRAEKGYII VGQDTDGTVT PGDAGLDWAV GKKKADFVGI RGLTRPDLVA
KGRKQLVGLK TKDPKVVLEE GAQIVEDPKQ AIPMKMIGHV TSSYWSENCG RSIALALVAG
GRDRMGDTLY VPMPNGVIEV EVTGMVFFDE TGGRLNG
//
