ID F8A507_CELGA Unreviewed; 744 AA.
AC F8A507;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Integral membrane protein {ECO:0000313|EMBL:AEI12110.1};
GN OrderedLocusNames=Celgi_1599 {ECO:0000313|EMBL:AEI12110.1};
OS Cellulomonas gilvus (strain ATCC 13127 / NRRL B-14078) (Cellvibrio gilvus).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Cellulomonadaceae;
OC Cellulomonas.
OX NCBI_TaxID=593907 {ECO:0000313|EMBL:AEI12110.1, ECO:0000313|Proteomes:UP000000485};
RN [1] {ECO:0000313|Proteomes:UP000000485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13127 / NRRL B-14078 {ECO:0000313|Proteomes:UP000000485};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Munk A., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Mead D., Brumm P.,
RA Woyke T.;
RT "Complete sequence of Cellvibrio gilvus ATCC 13127.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002665; AEI12110.1; -; Genomic_DNA.
DR RefSeq; WP_013883629.1; NC_015671.1.
DR AlphaFoldDB; F8A507; -.
DR STRING; 593907.Celgi_1599; -.
DR KEGG; cga:Celgi_1599; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_5_0_11; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000000485; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000485};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 201..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 583..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 669..689
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 695..714
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 234..364
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 744 AA; 77223 MW; 9332261FF7920070 CRC64;
MFARLGRVVA HHPRVIVVGW LVLAVLGYGL AVLGVHGESL FERLGTGEPT APGSESTQGR
AILEDADESG TSLTLVLSQV DPASTELADA LAPARTQLAE IPGVASVIDP LVLPDGVENP
AAAPLVSQRG DGFLVVVDLE PSLTGAQHAT AVDAVAARLR EVPAELRSVA PRVTGIVGGT
PLIVDEITSQ VEQDLRRGEA ITLPLALVVM VLVFGGFLAA AMPMAGALAS IAGGLATVLG
LSYVMEVDAS VVNVVTVLGL GLSIDYGLLI VSRFREELHR LVDHDEGRAA RRRRGDGAVA
AAVEATMATA GRTVAFSALT VGISIAALLV FPPQILRAIG AAGCAVVVIA VLTALTLVPA
LLALSGRRML RPGVLARVPG VRTVLARTSD DHAEEGAFSR LAARVQRHPW LVMGGVVVLL
GVLAAPLAHL ELRNSTTGLL PMGSAQREFV ETLATDYPAS TSPAVTVVAE TSLTQATAWA
DQVAELDAVA TVDPPAAAGP YVVIGVRPGS LDPGGAVARD AVQQIRALDP DFETWVTGQA
AAQIDFVAAL AGGAPWAALV VALATFALLF LMTGSFVIPV KALVTNALSL AASLGVLVWA
FQDGHLEGPL GFVSTGGVET YVLALVIAFG FGLAMDYEVF LLSRIKELHD QGVPTDEAVR
LGLQRSGRII TSAAAIIILV FAGFVSGQLL VIKEVGFALA VAVLIDATIV RLLLVPATMT
ILDRLNWWAP AWAARLHRRL EITH
//
