ID F8AI89_PYRYC Unreviewed; 127 AA.
AC F8AI89;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Putative multisubunit Na+/H+ antiporter {ECO:0000313|EMBL:AEH24322.1};
GN OrderedLocusNames=PYCH_06340 {ECO:0000313|EMBL:AEH24322.1};
OS Pyrococcus yayanosii (strain CH1 / JCM 16557).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=529709 {ECO:0000313|EMBL:AEH24322.1, ECO:0000313|Proteomes:UP000008386};
RN [1] {ECO:0000313|EMBL:AEH24322.1, ECO:0000313|Proteomes:UP000008386}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH1 / JCM 16557 {ECO:0000313|Proteomes:UP000008386};
RX PubMed=21705594; DOI=10.1128/JB.05345-11;
RA Jun X., Lupeng L., Minjuan X., Oger P., Fengping W., Jebbar M., Xiang X.;
RT "Complete genome sequence of the obligate piezophilic hyperthermophilic
RT archaeon Pyrococcus yayanosii CH1.";
RL J. Bacteriol. 193:4297-4298(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002779; AEH24322.1; -; Genomic_DNA.
DR RefSeq; WP_013905379.1; NC_015680.1.
DR AlphaFoldDB; F8AI89; -.
DR STRING; 529709.PYCH_06340; -.
DR GeneID; 10837210; -.
DR KEGG; pya:PYCH_06340; -.
DR eggNOG; arCOG03079; Archaea.
DR HOGENOM; CLU_101659_3_2_2; -.
DR OrthoDB; 19265at2157; -.
DR Proteomes; UP000008386; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007182; MnhB.
DR PANTHER; PTHR33932; NA(+)/H(+) ANTIPORTER SUBUNIT B; 1.
DR PANTHER; PTHR33932:SF4; NA(+)_H(+) ANTIPORTER SUBUNIT B1; 1.
DR Pfam; PF04039; MnhB; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..114
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 127 AA; 13876 MW; FD5EA23A509540C9 CRC64;
MKMSIVARTT TKLVSPFLVT YAIYLMLYST DAPGGGFQAG VVLAVAVVLL ITSHGYKKVR
KRFRKKVVGT FESAFGLAVV TLLLFVVALS LPPSNYYVVP FNVLVAVKVG SAFTLIFYTL
TAFLERD
//
