ID F8C4Z0_THEGP Unreviewed; 360 AA.
AC F8C4Z0;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin) {ECO:0000313|EMBL:AEH22774.1};
DE EC=1.2.7.7 {ECO:0000313|EMBL:AEH22774.1};
GN OrderedLocusNames=TOPB45_0672 {ECO:0000313|EMBL:AEH22774.1};
OS Thermodesulfobacterium geofontis (strain OPF15).
OC Bacteria; Thermodesulfobacteriota; Thermodesulfobacteria;
OC Thermodesulfobacteriales; Thermodesulfobacteriaceae;
OC Thermodesulfobacterium.
OX NCBI_TaxID=795359 {ECO:0000313|EMBL:AEH22774.1, ECO:0000313|Proteomes:UP000006583};
RN [1] {ECO:0000313|EMBL:AEH22774.1, ECO:0000313|Proteomes:UP000006583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OPF15 {ECO:0000313|EMBL:AEH22774.1,
RC ECO:0000313|Proteomes:UP000006583};
RX PubMed=23580711; DOI=10.1128/genomea.00162-13;
RA Elkins J.G., Hamilton-Brehm S.D., Lucas S., Han J., Lapidus A., Cheng J.F.,
RA Goodwin L.A., Pitluck S., Peters L., Mikhailova N., Davenport K.W.,
RA Detter J.C., Han C.S., Tapia R., Land M.L., Hauser L., Kyrpides N.C.,
RA Ivanova N.N., Pagani I., Bruce D., Woyke T., Cottingham R.W.;
RT "Complete genome sequence of the hyperthermophilic sulfate-reducing
RT bacterium Thermodesulfobacterium geofontis OPF15T.";
RL Genome Announc. 1:E0016213-E0016213(2013).
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DR EMBL; CP002829; AEH22774.1; -; Genomic_DNA.
DR RefSeq; WP_013909474.1; NC_015682.1.
DR AlphaFoldDB; F8C4Z0; -.
DR STRING; 795359.TOPB45_0672; -.
DR KEGG; top:TOPB45_0672; -.
DR PATRIC; fig|795359.3.peg.682; -.
DR eggNOG; COG0674; Bacteria.
DR HOGENOM; CLU_017038_0_0_0; -.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000006583; Chromosome.
DR GO; GO:0043807; F:3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR43088; SUBUNIT OF PYRUVATE:FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR43088:SF1; SUBUNIT OF PYRUVATE:FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:AEH22774.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006583}.
FT DOMAIN 17..228
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 249..328
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 360 AA; 39808 MW; 2B5C7699A12CAE59 CRC64;
MKVKKILAKG VEAIALGALE ADCKCYFGYP ITPQNEIPEI MARELPKRGG VFLQAESEIA
AINMLLGACA TGTRAMTSSS SPGISLMCET FSYIAAQELP AVIVNVMRGG PGLGGIEASQ
GDYFQAVKGS GHGDFHFLVL APYNAQEAYE LTAKAFELAE KYRNPVMILS DAVLGQMKEP
VVLKKLKIKK YPNETWALTG AKNRPSRIIR SLFLSSQELK ERNLNLMKKY KKMEKDVLYE
AKIEEEDQVI VVAFGSMARI AKETCINLKK KGYPVGFFRP ITLFPFPSKA IKALLKNEKK
PKKFIVAELN CGQMVEDVKL SVDGKAEVIS LFFPPSVIPF PEELEKRIKK CIKPSSSQKV
//
