ID F8DGQ6_STREP Unreviewed; 548 AA.
AC F8DGQ6;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein {ECO:0000313|EMBL:AEH56666.1};
GN OrderedLocusNames=HMPREF0833_11635 {ECO:0000313|EMBL:AEH56666.1};
OS Streptococcus parasanguinis (strain ATCC 15912 / DSM 6778 / CIP 104372 /
OS LMG 14537).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=760570 {ECO:0000313|EMBL:AEH56666.1, ECO:0000313|Proteomes:UP000001502};
RN [1] {ECO:0000313|Proteomes:UP000001502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15912 / DSM 6778 / CIP 104372 / LMG 14537
RC {ECO:0000313|Proteomes:UP000001502};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RT "Complete sequence of Streptococcus parasanguinis strain ATCC 15912.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002843; AEH56666.1; -; Genomic_DNA.
DR RefSeq; WP_013904468.1; NC_015678.1.
DR AlphaFoldDB; F8DGQ6; -.
DR KEGG; scp:HMPREF0833_11635; -.
DR HOGENOM; CLU_020473_6_3_9; -.
DR Proteomes; UP000001502; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR42713; HISTIDINE KINASE-RELATED; 1.
DR PANTHER; PTHR42713:SF2; TWO-COMPONENT SENSOR KINASE YESM; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AEH56666.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 274..327
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 548 AA; 62842 MW; 46B5B73DAFF403D8 CRC64;
MKRIWLSTLL KFYAYVMVAI LTIMGLVVAG ISWKNQQADA DRIAQRVLTE VVTDLETSYQ
RVTQEGRSLV ENPAKLEGVY RYFTLTPSEY ETWRLNAQFP SYIQLSLHKN IDSLYLSNKN
IEGIDVTLSD YKTVFVSTRQ SKGGKQVSAD HYKAPVTAIP VPLTDPTTGA GVGIAYMTLD
QEILTATIDN ARGDLPIAVR IFTPFGKEMY HEGDKGQSKD IKWQTRSTIY GYKVDVAVSE
SYLVKKGLAN LTTFLSIAFL IFLILYLLLG QIFKNYRRQV LDLVDTMNLI SQGDSERRID
TSTKDQELLV IGNMINTMLD NMDKNIRDID QLQLSQKDAN MRALQAQINP HFMYNTLEFI
RMYAVMQEQD ELGDIIYEFS SLLRNNISDE RVTTVENELE FCRKYSYLCM VRYPKSIAYG
FKIDPGLEKM KIPKFTIQPL VENYFAHGVD HKRKDNVISV KVLQGEGQVM ILVSDNGRGM
EEEQLEKIQE ILANRNPRSE IEEKSGRQSI GIVNVHERML LYFGDRYHIH VFSQPHHGVT
YTITIQDE
//
