ID F8E3X8_FLESM Unreviewed; 339 AA.
AC F8E3X8;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000313|EMBL:AEI15480.1};
DE EC=2.5.1.54 {ECO:0000313|EMBL:AEI15480.1};
GN OrderedLocusNames=Flexsi_1842 {ECO:0000313|EMBL:AEI15480.1};
OS Flexistipes sinusarabici (strain ATCC 49648 / DSM 4947 / MAS 10).
OC Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC Flexistipitaceae; Flexistipes.
OX NCBI_TaxID=717231 {ECO:0000313|EMBL:AEI15480.1, ECO:0000313|Proteomes:UP000006621};
RN [1] {ECO:0000313|EMBL:AEI15480.1, ECO:0000313|Proteomes:UP000006621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4947 / MAS 10 {ECO:0000313|Proteomes:UP000006621};
RX PubMed=22180813; DOI=10.4056/sigs.2235024;
RA Lapidus A., Chertkov O., Nolan M., Lucas S., Hammon N., Deshpande S.,
RA Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA Pagani I., Ivanova N., Huntemann M., Mavromatis K., Mikhailova N., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Brambilla E.M., Rohde M.,
RA Abt B., Spring S., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Woyke T.;
RT "Genome sequence of the moderately thermophilic halophile Flexistipes
RT sinusarabici strain (MAS10).";
RL Stand. Genomic Sci. 5:86-96(2011).
RN [2] {ECO:0000313|Proteomes:UP000006621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4947 / MAS 10 {ECO:0000313|Proteomes:UP000006621};
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Chertkov O.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Flexistipes sinusarabici DSM 4947.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002858; AEI15480.1; -; Genomic_DNA.
DR RefSeq; WP_013886948.1; NC_015672.1.
DR AlphaFoldDB; F8E3X8; -.
DR STRING; 717231.Flexsi_1842; -.
DR KEGG; fsi:Flexsi_1842; -.
DR eggNOG; COG2876; Bacteria.
DR HOGENOM; CLU_062599_0_0_0; -.
DR OrthoDB; 9780456at2; -.
DR Proteomes; UP000006621; Chromosome.
DR GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016832; F:aldehyde-lyase activity; IEA:InterPro.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006218; DAHP1/KDSA.
DR InterPro; IPR041071; DAHP_snth_FXD.
DR InterPro; IPR006268; DAHP_syn_2.
DR NCBIfam; TIGR01361; DAHP_synth_Bsub; 1.
DR PANTHER; PTHR43018; PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE; 1.
DR PANTHER; PTHR43018:SF2; PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE; 1.
DR Pfam; PF18152; DAHP_snth_FXD; 1.
DR Pfam; PF00793; DAHP_synth_1; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006621};
KW Transferase {ECO:0000313|EMBL:AEI15480.1}.
FT DOMAIN 1..67
FT /note="DAHP synthase ferredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18152"
FT DOMAIN 84..324
FT /note="DAHP synthetase I/KDSA"
FT /evidence="ECO:0000259|Pfam:PF00793"
SQ SEQUENCE 339 AA; 37291 MW; D35DE558EC7040BF CRC64;
MIIVLKPEAT AENRDFVVDR LKSLGFQTHI SEGEERTIIG AIGDERQLRD RPLSSLPGVE
KVVPILKPYK LVSKDFKKTN SEISINGIKI GGKHTTVMAG PCSVENREML FEIVDKIYDA
GARVLRGGAF KPRTSPYSFQ GLGEEGLKYL REAADSKGML VVTELMDPRD IDLICKYADI
IQIGARNMQN FRLLKEVGKS GHPVLLKRGM SATIKEFLMA AEYIASEGNL DIILCERGIR
TFETETRNTL DLSAIPVIKN ASHLPVVVDP SHGTGRRDCI LPMAQAAIAA GADGLIIEVH
PNPAEAMSDG DQSITPDEFA TLMKRIKIIS ATLERHLEE
//
