ID   F8GEQ1_NITSI            Unreviewed;       789 AA.
AC   F8GEQ1;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=Probable phosphoketolase {ECO:0000256|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000256|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=Nit79A3_0036 {ECO:0000313|EMBL:AEI99944.1};
OS   Nitrosomonas sp. (strain Is79A3).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=261292 {ECO:0000313|EMBL:AEI99944.1};
RN   [1] {ECO:0000313|EMBL:AEI99944.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Is79A3 {ECO:0000313|EMBL:AEI99944.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Lu M., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Pagani I., Bollmann A., Norton J.,
RA   Suwa Y., Klotz M., Stein L., Laanbroek H., Arp D., Woyke T.;
RT   "Complete sequence of Nitrosomonas sp. Is79A3.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964,
CC         ECO:0000256|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623,
CC       ECO:0000256|HAMAP-Rule:MF_01403}.
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DR   EMBL; CP002876; AEI99944.1; -; Genomic_DNA.
DR   AlphaFoldDB; F8GEQ1; -.
DR   STRING; 261292.Nit79A3_0036; -.
DR   KEGG; nii:Nit79A3_0036; -.
DR   eggNOG; COG3957; Bacteria.
DR   HOGENOM; CLU_013954_2_0_4; -.
DR   OrthoDB; 9768449at2; -.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd02011; TPP_PK; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR   PANTHER; PTHR31273:SF0; PHOSPHOKETOLASE-RELATED; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_01403};
KW   Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052, ECO:0000256|HAMAP-
KW   Rule:MF_01403}.
FT   DOMAIN          9..368
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09364"
FT   DOMAIN          583..784
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09363"
SQ   SEQUENCE   789 AA;  88821 MW;  4B727E01B5CBD2A5 CRC64;
     MKKNTKLLSP ELLHKMDAYW RAANYLSVGQ IYLYDNPLLK QPLKLAHIKP RLLGHWGTTP
     GLNFIYVHLN RIIKEHDLNV IYITGPGHGG PGLVANTYLE GTYSEVYPNI SQDEDGMQRL
     FKQFSFPGGI PSHVAPETPG SIHEGGELGY SLSHAFGAAF DNPGLLVACV VGDGEAETGP
     LATSWHSNKF LNPVHDGAVL PILHLNGYKI AGPTVLARIP CDELEALFRG YGYTPYFIEG
     DDPLEMHQRM AATLDAVIAN IQSIQRDART HGFTKRPHWP MIILRSPKGW TGPKVVDGKP
     TEGTFRSHQV PMGDMSQPGH VKILEKWLKS YRPQELFDET GKLLAELAEL APQGARRMGA
     NPHANGGMLL RDLRLPDFRD YAVKVANPGT VSAEATRTQG EFIRDVVKLN ATNFRVFSPD
     ETASNRWGAV FEVTNRCSTA EIVPGDDHVA PDGRVMEMLS EHQCEGWLEG YLLTGRHGFF
     SCYEAFIHII DSMFNQHAKW LKVANEIPWR RPIASLNYLL SSHVWRQDHN GFSHQDPGFI
     DHVINKKAEI IRIYLPPDAN TLLSVTDHCL RSRNYVNVIV AGKQPQPQWL DMDAAIKHCT
     AGIGIWEWAS NDQGEEPDVV MACAGDAPTI ETLAAVELLW KHFPELKIRV INVVDLMSLQ
     PQSEHPHGLS DKDFDGLFTK DKPIIFAYHG YPWLIHRLTY RRTNHDNLHV RGYKEEGTTS
     TPFDMVVMND LDRFHLVADV IDRVPQLGSR AAYVKQAIRD KLIEHKQYIN QYGEDMPEIR
     NWKWKGSSV
//