ID F8GR35_CUPNN Unreviewed; 315 AA.
AC F8GR35;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Shikimate dehydrogenase AroE {ECO:0000313|EMBL:AEI80780.1};
DE EC=1.1.1.25 {ECO:0000313|EMBL:AEI80780.1};
GN Name=aroE2 {ECO:0000313|EMBL:AEI80780.1};
GN OrderedLocusNames=CNE_2c18240 {ECO:0000313|EMBL:AEI80780.1};
OS Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453
OS / N-1) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1042878 {ECO:0000313|EMBL:AEI80780.1, ECO:0000313|Proteomes:UP000006798};
RN [1] {ECO:0000313|EMBL:AEI80780.1, ECO:0000313|Proteomes:UP000006798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1
RC {ECO:0000313|Proteomes:UP000006798};
RX PubMed=21742890; DOI=10.1128/JB.05660-11;
RA Poehlein A., Kusian B., Friedrich B., Daniel R., Bowien B.;
RT "Complete genome sequence of the type strain Cupriavidus necator N-1.";
RL J. Bacteriol. 193:5017-5017(2011).
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DR EMBL; CP002878; AEI80780.1; -; Genomic_DNA.
DR AlphaFoldDB; F8GR35; -.
DR KEGG; cnc:CNE_2c18240; -.
DR HOGENOM; CLU_044063_4_0_4; -.
DR Proteomes; UP000006798; Chromosome 2.
DR GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd01065; NAD_bind_Shikimate_DH; 1.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR013708; Shikimate_DH-bd_N.
DR InterPro; IPR022893; Shikimate_DH_fam.
DR PANTHER; PTHR21089; SHIKIMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21089:SF34; SHIKIMATE DEHYDROGENASE (NADP(+)); 1.
DR Pfam; PF08501; Shikimate_dh_N; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AEI80780.1}.
FT DOMAIN 51..132
FT /note="Shikimate dehydrogenase substrate binding N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08501"
SQ SEQUENCE 315 AA; 33461 MW; 4773C666CFA458A4 CRC64;
MRSLIAQYGV KDAWLAGSRP LISGHRNAPG PAARLTNTMI NGKTTLIPHL GYPTESFKAP
MIYNPWFAQQ GIDAVVVPMG VKPDNYAEVF RSLFRLTNIR GALVTMPHKV ATLELVDELT
PAARIAGACN AVLRRDDGTL VGDQFDGAGF VRGIVRKGCR PEGARAIVSG SGGVGSAIAA
SLAQAGVAEL ALFDAREGAA RALARRLAEH YPALRVSTGS DDPQGFDVVV NATPLGMHAG
DPLPFDVARI APGAMVGEVV MKHEYTPFLE AALARGCKVQ VGTDMLFEMI PAYLEFFGYG
TATPEALRAV AQIRY
//
