ID F8IIJ9_ALIAT Unreviewed; 548 AA.
AC F8IIJ9;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:AEJ43331.1};
GN Name=acs {ECO:0000313|EMBL:AEJ43331.1};
GN OrderedLocusNames=TC41_1395 {ECO:0000313|EMBL:AEJ43331.1};
OS Alicyclobacillus acidocaldarius (strain Tc-4-1) (Bacillus acidocaldarius).
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Alicyclobacillus.
OX NCBI_TaxID=1048834 {ECO:0000313|EMBL:AEJ43331.1, ECO:0000313|Proteomes:UP000000292};
RN [1] {ECO:0000313|EMBL:AEJ43331.1, ECO:0000313|Proteomes:UP000000292}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tc-4-1 {ECO:0000313|EMBL:AEJ43331.1,
RC ECO:0000313|Proteomes:UP000000292};
RX PubMed=21914900; DOI=10.1128/JB.05709-11;
RA Chen Y., He Y., Zhang B., Yang J., Li W., Dong Z., Hu S.;
RT "Complete Genome Sequence of Alicyclobacillus acidocaldarius Strain Tc-
RT 4-1.";
RL J. Bacteriol. 193:5602-5603(2011).
RN [2] {ECO:0000313|Proteomes:UP000000292}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tc-4-1 {ECO:0000313|Proteomes:UP000000292};
RA Chen Y., He Y., Dong Z., Hu S.;
RT "The complete genome sequence of Alicyclobacillus acidocaldarius sp. Tc-4-
RT 1.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP002902; AEJ43331.1; -; Genomic_DNA.
DR RefSeq; WP_014464206.1; NC_017167.1.
DR AlphaFoldDB; F8IIJ9; -.
DR STRING; 1048834.TC41_1395; -.
DR KEGG; aad:TC41_1395; -.
DR PATRIC; fig|1048834.4.peg.1329; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_59_10_9; -.
DR OrthoDB; 9765680at2; -.
DR Proteomes; UP000000292; Chromosome.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR CDD; cd05972; MACS_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AEJ43331.1}.
FT DOMAIN 28..388
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 438..525
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 548 AA; 61271 MW; B108CBFAE681AB72 CRC64;
MEPTQTAAFA DLLAPDVFNI AGAILDRDES RRALVWRSET GAKRTLTYGE LRRESLRLAH
ALHDLGLRKG DRVLVLMPRR PETYAVYLAI LSIGAVVLPG SELLMPNDIA YRLKHAEAKG
VIAHAALAER AEAAIAEAPW VQLRVVVEGS REGFLAYEDL VRGAPGEWDV VPTRRDDLAF
LSYTSGTTGY PKGVMHVHGW AYAHWHIAAK RWLGIEPDDV VWATAGPGWA KWIWSPFVAT
LMSGATGFHY GGRFDAETFL RLIDEEGVNV LCATPTEYRM MAKVDGLDRF RLSSLRQAVS
AGEPLNREVI DTFRRHFQIT VRDGYGQTEN TLLVATCVDT EVRPGSMGLP TVEGAVDIVD
EEGRSLPPGQ VGDIAVRRDF PALFRGYYKD EERTVAQFRG AWYITGDRAE KDQDGYLWFS
GRADDIIISA GYTIGPFEVE DALVKHPLVR ECAAVSSPDE VRGAIVKAFV VLKDLNLHRE
LASDAERREA LVRELQEHVK RITAPYKYPR AIEFVEDLPK TTSGKIRRVE LREREWKRHR
ELNAGQGG
//
