ID F8KXZ6_PARAV Unreviewed; 383 AA.
AC F8KXZ6;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Ribosomal RNA large subunit methyltransferase L {ECO:0000313|EMBL:CCB85732.1};
DE EC=2.1.1.173 {ECO:0000313|EMBL:CCB85732.1};
GN Name=rlmL-A {ECO:0000313|EMBL:CCB85732.1};
GN OrderedLocusNames=PUV_07820 {ECO:0000313|EMBL:CCB85732.1};
OS Parachlamydia acanthamoebae (strain UV7).
OC Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Parachlamydiaceae;
OC Parachlamydia.
OX NCBI_TaxID=765952 {ECO:0000313|EMBL:CCB85732.1, ECO:0000313|Proteomes:UP000000495};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UV7;
RA Collingro A., Tischler P., Weinmaier T., Penz T., Heinz E., Brunham R.C.,
RA Read T.D., Bavoil P.M., Sachse K., Kahane S., Friedman M.G., Rattei T.,
RA Myers G.S.A., Horn M.;
RT "Unity in variety -- the pan-genome of the Chlamydiae.";
RL Mol. Biol. Evol. 0:0-0(2011).
RN [2] {ECO:0000313|EMBL:CCB85732.1, ECO:0000313|Proteomes:UP000000495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UV7 {ECO:0000313|Proteomes:UP000000495};
RX PubMed=21690563; DOI=10.1093/molbev/msr161;
RA Collingro A., Tischler P., Weinmaier T., Penz T., Heinz E., Brunham R.C.,
RA Read T.D., Bavoil P.M., Sachse K., Kahane S., Friedman M.G., Rattei T.,
RA Myers G.S., Horn M.;
RT "Unity in variety--the pan-genome of the Chlamydiae.";
RL Mol. Biol. Evol. 28:3253-3270(2011).
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DR EMBL; FR872580; CCB85732.1; -; Genomic_DNA.
DR RefSeq; WP_006342268.1; NC_015702.1.
DR AlphaFoldDB; F8KXZ6; -.
DR STRING; 765952.PUV_07820; -.
DR KEGG; puv:PUV_07820; -.
DR eggNOG; COG0116; Bacteria.
DR HOGENOM; CLU_032119_3_0_0; -.
DR OrthoDB; 9809404at2; -.
DR Proteomes; UP000000495; Chromosome.
DR GO; GO:0052915; F:23S rRNA (guanine(2445)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CCB85732.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000495};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:CCB85732.1}.
FT DOMAIN 51..162
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 383 AA; 43297 MW; 6BE826CD2A1EE9FC CRC64;
MGYQNLASAE LFVTCSQGLE PLLIEELQEL SFENAHPGFR GVFVKIKDLS DIYRINYNSR
IASRVLFPLT TFNCYDQKAL YRGASQFNWI PFFRKGMTFA IDSNVNHRLI RNSLFAAQVV
KDAICDQLRE KFGERPNIDV KNPDIQLNLF IQGNTAILSL DTSGAPLHKR GYRLDSVEAP
MQENLAAAIL RLANYKKEEI MCDPCCGSGT LLIEAALMAS QTPPGFLRKD WGFMRFPEFS
ASDWLKVKME ADQKRQPIPK GHLFGVEINK NAVRVSKTNI RAAGFLSEIE VVQGDFREWT
PSVLPTLLVT NPPHGKRLDF AEDLRPLYRS IGDFMKQKMA KPARGFVFTG NLDLTKEVGL
AAKRRHVLHS GGVESRLLEF DVY
//
