ID F9WDS8_TRYCI Unreviewed; 451 AA.
AC F9WDS8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=WGS project CAEQ00000000 data, annotated contig 2401 {ECO:0000313|EMBL:CCD15432.1};
GN ORFNames=TCIL3000_0_59540 {ECO:0000313|EMBL:CCD15432.1};
OS Trypanosoma congolense (strain IL3000).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Nannomonas.
OX NCBI_TaxID=1068625 {ECO:0000313|EMBL:CCD15432.1, ECO:0000313|Proteomes:UP000000702};
RN [1] {ECO:0000313|Proteomes:UP000000702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL3000 {ECO:0000313|Proteomes:UP000000702};
RA Jackson A.P., Berry A., Allison H.C., Burton P., Anderson J., Aslett M.,
RA Brown R., Corton N., Harris D., Hauser H., Gamble J., Gilderthorp R.,
RA McQuillan J., Quail M.A., Sanders M., Van Tonder A., Ginger M.L.,
RA Donelson J.E., Field M.C., Barry J.D., Berriman M., Hertz-Fowler C.;
RT "Divergent evolution of antigenic variation in African trypanosomes.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCD15432.1, ECO:0000313|Proteomes:UP000000702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL3000 {ECO:0000313|EMBL:CCD15432.1,
RC ECO:0000313|Proteomes:UP000000702};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC family. {ECO:0000256|ARBA:ARBA00010884}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCD15432.1}.
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DR EMBL; CAEQ01001909; CCD15432.1; -; Genomic_DNA.
DR AlphaFoldDB; F9WDS8; -.
DR VEuPathDB; TriTrypDB:TcIL3000_0_59540; -.
DR OMA; LDWHGPH; -.
DR OrthoDB; 1655372at2759; -.
DR Proteomes; UP000000702; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR PANTHER; PTHR10794; ABHYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10794:SF63; ALPHA_BETA HYDROLASE 1, ISOFORM A; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000702};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 451 AA; 50510 MW; 72FA504F36EB444F CRC64;
MYTFFFCSSL QIAMRASGVG PFAWPMSSLK ERMLFLALHV MVHICAIYLW SLVRATMNMI
SRRKSDEDHG KIEVLTNGAK AREFFSLGAV ESLWYHSPPY NGKINTILSA LRPNWPIAYN
REVVDGIDGN PICLDWLLAD ETRGDGRGIL VILPGLASWS QTNYVQRCVL QAHRYGIHCC
VFNCRGLGDT PLTTPRLISA SWTGDLHKIF STALSRDVLS SRFGAAAENI WGAGFSLGGV
IMTKFLKECG NTDKTPSPLD AAIIINSPLD MEETSRTLNE PKNAMYQRRM ISNVIQFVSK
HIDVLKNVAE VDVKDFDNDL LKFMKSLRSL QEFDLYINAP HNGFSTVREF YDAVNVLTSL
KHCKIPMLCL IAQDDPVIGL VPRDSLTDVI SKNDLVAFVR FPYGGHLGFC KTPLEEWNGD
PSLMEIFVCD LISSRGHTKS EKEQSGCESL Y
//
